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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

invigorate
新的一年,产自利比亚的原油可能再度流入市场。受国内冲突影响,2013年利比亚的原油出口遭遇重大问题。此外,伊拉克原油产量也将增加。就连已多年被全球市场拒之门外的伊朗也有望重返市场,前提是该国与西方国家达成协议,放松对旨在限制该国发展核武器的制裁。所有这些可能会使中东地区原油日产量增加200万至300万桶。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Hong Kong has topped the list for the past seven years -- since its first appearance in the survey.
adj. 非常坚硬的,强硬的,固执的 n. 坚硬无比之物

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Actress in a Mini-Series or Movie: Sarah Paulson, “The People v. O. J. Simpson: American Crime Story”

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

The Cnzz.com report states that almost two-thirds of China's 338 million Web users are now online game players. The online game industry, which currently accounts for more than half of the total Internet economy, will see strong annual growth at a rate of 20% in future years, the report says.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Gov. Ricardo Rossello, 37, proposed several measures aimed at alleviating the crisis shortly after he was sworn in at midnight. Among them is a proposal to hold a referendum that would ask voters whether they prefer statehood or independence. Many have argued that Puerto Rico’s political status has contributed to its decade-long crisis that has prompted more than 200,000 people to flee to the U.S. mainland in recent years.
Going into the debate at Lynn University in Boca Raton, Florida, Obama had an inbuilt advantage on foreign policy and security. As president, with access to daily briefings by intelligence analysts, diplomats and generals, he is better briefed and it showed as he dominated Romney in the first half of the debate.
他说:“比如说,如果他们拖延从韩国进口的海关流程并采取对韩国商品的其他报复举措,韩国政府对此将无能为力。”
May the bright and festive glow of New Year candle warm the days all the year through. Hoping you will have a wonderful time enjoying New Year that is happy in every way.愿明亮喜庆的新年烛光温暖一年中的每个日日夜夜,祝你欢欢喜喜度新年!

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

But I expect other banks to follow suit. Any effort to keep good people fresh and engaged, without paying them more, should be up for consideration.
而在非手术整形中,注射肉毒杆菌和激光脱毛依然是最受欢迎的。
我们的前路应有尽有,我们的前路一无所有……
房价尽管缓慢却持续不断地增长与近期数据走势一致,这些数据显示10月份对房地产投资有所增加,新一轮限购对录得的销售几乎没有任何负面影响。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

9. HitTail

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 北京回龙观一周整治群租房百余套
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

vigor(n 精力;活力)

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

6. 谷歌搜索广告关键词规划工具
The actor - who is heavily tipped for his first Oscar this year - won the gong for best actor in a film drama for his role in The Revenant, beating rivals including Eddie Redmayne who was nominated for The Danish Girl.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

22岁的吉吉·哈迪德和21岁的贝拉·哈迪德也是首次跻身榜单,分别位列榜单的第五位和第九位,吉吉·哈迪德的收入为950万美元,她的妹妹贝拉·哈迪德的收入为600万美元。
华盛顿(市场观查者)—美国经济2014年迎来了自二战后最曲折的复苏而且年末能源方面又遇到了大的波折,但是2015年美国经济将披荆斩棘变得更好。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

杜邦自称“金鹰”,有着独特的,鹰隼般的外形。设计师们想塑造出那个外形,但又不想弄得跟杜邦本人一模一样。
还有些电视剧不如人们最初预料的好,不过仍有吸引力,最显眼的是映时频道的《婚外恋》,它一开始看起来像汉普顿斯式黑色电影,后来变成了法国艺术电影。剧中的罪行与过于缓慢的节奏以及《罗生门》(Rashomon)式的讲述方式不太相称,不过该剧在最后几集势头大涨,悬念丛生。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

delicate
每个伟大的侦探都需要专属于自己的经典故事。对于福尔摩斯而言,这个故事是《巴斯克维尔的猎犬》。对于阿加莎?克里斯蒂笔下龟毛的比利时侦探赫克尔?波洛而言,这个故事是《东方快车谋杀案》——故事讲述了一个嗜血的恶棍在驶向巴尔干半岛的列车上杀死了一个有钱的商人。真相果真是如此吗?西德尼?吕美特曾在1974年将该故事拍成了一部备受喜爱的电影,强大的演员阵容包括肖恩?康纳利、英格丽?褒曼和阿尔伯特?芬尼(饰演侦探波洛)。如今肯尼思?布拉纳自己戴上了侦探波洛的大胡子,披挂上阵,同时又担当幕后导演。这部新版电影的演员有约翰尼?德普、黛西?雷德利、米歇尔?菲佛、佩内洛佩?克鲁斯和朱迪?丹奇。这个故事还能挖掘出什么新内容呢?也许会有。不过,即使没有,阿婆的粉丝也肯定会去看。这部电影将于11月3日在英国上映,11月10日在美国、中国和土耳其上映,11月30日在中国香港和新加坡上映。(资料来源:二十世纪福克斯电影公司)
"In the aftermath of recessions, there's always a period of jobless recovery," says John Challenger, CEO of global outplacement firm Challenger Gray & Christmas. "We're certainly not optimistic about seeing much improvement in the unemployment rate in 2010."
《迈耶罗维茨的故事》

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

办公室总有一两个让人让大多数人都无法容忍的人,但是如果你不喜欢大多数的同事,那么你的工作就会变得不愉快因为你不得不整天和他们在一起工作。如果你再也不能容忍他们,试试找一个你能够和里面的职员和平相处的公司了。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The Crown
[iks'p?uzd]

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Much joy to you in the up coming year. May the warmest wishes, happy thoughts and friendly greetings come at New Year and stay with you all the year through.让温馨的祝愿、幸福的思念和友好的祝福,在新年来到你身边,伴你左右。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

"绝望主妇"伊娃与老公的性感广告宣传照

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

该项目曾在2006年荣获亚军,并在2008年斩获冠军头衔。
2016年,担忧和愤怒主导了英国和美国这两个最重要、稳定、悠久的民主政体的政治情绪。
本土冠军
reg统治,ulate-管制

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

不过,中国的手机制造商却在2016年实现了崛起。华为出货量同比增长了30.2%,达到了1.393亿台,再次排在全球第三。
Despite relatively low comparative competition earnings and salary, the pair were the two highest earners in regards to endorsement deals last year, with 17-time Grand Slam champion Federer earning pound 41 million.
最近,无人驾驶汽车的新闻屡见报端,它也叫做自动驾驶汽车。谷歌的自动驾驶汽车是此行业的领头羊,已行驶48万千米(30万英里),仅发生过两次交通事故,还都是人为因素造成的。事实上,无人驾驶汽车并不是新奇事物,早在达·芬奇发明以弹簧发条作驱动带内置预设程序的马车时,自动驾驶的概念便名噪一时。
CONTACT: Staci Donegan and Peter Westley, Celia Dunn Sotheby’s International Realty, (912) 247-2052 / (912) 660-5169; celiadunnsir.com
小编碎碎念:华裔球员林书豪的一夜爆红,让因病缺阵的尼克斯当家球星小甜瓜安东尼颇有几分“躺着也中枪”的无辜感。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

corn
[in'tendid]

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

但是,这一情况在两年前发生了变化,清华大学首次跻身前20名,2016年排名第18位。去年,北京大学也跻身前20名。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Sales & Marketing

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

pro向前+duct引导,带来+ive→生产的;多产的
Debrecen is Hungary's second largest city after Budapest, and the heart of low-cost Hungary.
在过去的二十年里,几起校园中毒事件引发了群众对学生心理发展及帮助的争论和关注。
“That’s the difference between tweeting from your couch and governing the country. If you govern the country, you have to take sensible decisions, and that isn’t sensible,” Mr Rutte replied.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

奥巴马在俄亥俄州、威斯康星州、爱荷华州、宾夕法尼亚州和新罕布什尔州都以微弱的优势超过了罗姆尼,而在这些地方罗姆尼都曾经前往发表过演讲。根据网络数据,唯一被罗姆尼的风采征服的摇摆州是北卡罗来纳州。
3、Negativity
The programme entered the ranking in second place in 2006 and was ranked top in 2008.
Rare pictures have been released showing the ancient sex toys that once belonged to the Chinese royals and aristocrats.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

n. 运输,运输系统,运输工具
另一位对时尚颇有野心的人就是温妮·哈洛,她在这场举世闻名的节庆活动的第一天即崭露头角。这位患有白斑病的加拿大模特几乎抢了艾米莉的风头,她用自己优雅的舞会礼服吸引了众人的关注。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

[k?n'vi:nj?nt]
If he wins the primary, he would face off against first-term Republican Gov. Phil Scott, 59.
在动画电影行业执迷于翻拍让观众有共鸣的老故事时,皮克斯却总能尝试新事物,把观众带到从未踏足的新领域。《寻梦环游记》由《玩具总动员3》导演李?昂克里奇执导,该片的视觉效果基于墨西哥的亡灵节。故事讲述了一个名叫米格尔的小男孩崇拜传奇吉他手欧内斯托?德?拉?克鲁兹,想学习如何能弹奏得和他一样好。于是他就像奥德赛一样踏上了改造性的自我发现之旅,进入死亡之地寻找那位已去世多年的偶像,还受到了一些关于创造力本质的教导。《寻梦环游记》是否能达到皮克斯2015年杰作《头脑特工队》的高度尚未可知,但这部电影绝对是一场视觉盛宴。该片将于11月15日在法国上映,11月22日在美国、克罗地亚和菲律宾上映,11月30日在以色列上映。(资料来源:迪士尼/皮克斯)
Industrial production expanded 1.4 per cent month-on-month in October, the quickest pace since a 4.1 per cent rise in January. It was better than the 1.1 per cent gain in September, but still fell short of economists' expectations for a gain of 1.8 per cent.
['w?:θ'wail]

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

In fact, academic research suggests that other economic and social transformations unfolding at the same time have led many people to anchor themselves more fully in their whiteness — even as whiteness itself has lost currency.
历史会这样回首2012年:这一年,中国“第五代”领导层亮相,同时中国经济转向较低速增长的轨道。这种转变发生的背景,将是一系列令人畏惧的国内挑战——不断增加的社会不安定,不断扩大的收入差距,以及生态和人为的灾难——加上不断升级的外部紧张,这源于美国重新转向亚洲,同时亚太邻国对中国的经济崛起越来越感到忧虑。
1. “Timbuktu”(Abderrahmane Sissako)

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Her predecessor David Cameron placed fifth in CNNMoney's previous ranking in March 2015 with his salary of £142,500, then worth $214,800. May is only seventh.
The private Facebook group chat that led to offers of admission being rescinded was named, at one point, "Harvard memes for horny bourgeois teens", the Crimson reported.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 谁来赋予照明的“灵魂”?
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 深圳禁用不合格装饰装修材料
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

保罗在高中是一个相当矮小的后卫,这也是他有“排斥一切”思想的原因。CP3是NBA中最难对付和最棘手的球员,而他也必须如此,因为他知道自己还不是强者之一。
税:2014年约为16866美元(约合人民币10.8万元)
Forex reserves fell $87bn in November, near the record $94bn decline suffered in August — the same month that the central bank surprised global markets by allowing the renminbi to depreciate by 3 per cent in three days.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

We will continue to encourage people to start businesses and make innovations.
摆放一个小书架,用来放自己的杂志或报纸,这一方面有利于节省空间,另一方面可以让你能够很快找到自己想要的东西。
6、《招魂2:恩菲德的骚灵》

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

tempor时间+ary表形容词,“…的”→短暂的

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

去年,外国机器人市场向我国售出103191台机器人,同比增长71.9%。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

10) You’re Right: Want to get someone’s attention? Tell him that he’s right. Once you yield the high ground, it’s much easier for the other party to swallow that the right plan and sentiment can’t always overcome the absurdities and restraints we face every day.
愿你度过最美好的新年!

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Harvard Business School, London Business School (LBS) and MIT Sloan School of Management, three of the MBA ranking’s longstanding heavyweights, all lost ground to their competitors. Harvard drops two places to fourth, the first time in nine years that the Boston school has been outside the top three. London Business School falls three places to sixth, its lowest position in 14 years. MIT Sloan School of Management falls to 13th place, the first time in 10 years that it has been outside the top 10.
沙特阿美(Saudi Aramco)会在外国公开上市吗?
全国工商联汽车经销商会数据显示,自2014年进口现代中国经销商网络已经缩减了一半。
发行于2013年的《炫富帮》是一部语带讽刺的犯罪剧情片,记录了一帮好莱坞山高中生的冒险,他们偷到了当地名人的家里。少年们进入梅根·福克斯和帕丽斯·希尔顿这样的偶像家,偷走现金、衣服、手袋和珠宝,用来模仿杂志上让他们羡慕的奢华生活。在朋友圈炫耀战利品的照片后,他们终于被抓进了监狱。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

另一名来自美国的毕业生写道,来自世界各地的知识的丰富性和深度为课程带来了巨大的价值,他补充称,“鉴于这里汇聚着众多的文化和经验,有关贿赂的课堂道德讨论不像典型的美国学校那样枯燥。”
威尼斯被普遍认为是世界上最浪漫的城市之一,也是许多游客必来的水上城市。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

“It comes down to answering these questions: how do you continue to iterate the platform, how do you continue to augment the team, and how do you build a tapestry of alliances with partners that will accelerate your growth?” Case said.
['pail?t]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

这是光明的季节,也是黑暗的季节……

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The dollar value of China’s exports fell markedly more than expected last month and import growth more than halved, while revisions to November data erased what had appeared to be a long-hoped-for return to growth for outbound shipments.
If you plan to visit Brazil for the Olympic games, and to focus on sport and having fun, Google has you covered. In anticipation of the 2016 Rio Olympics, the search giant is bringing the 'Explore' feature to Brazil Maps.
The largest flawless vivid blue diamond in the world is to go on sale today at Christie's auction house.
在《醉乡民谣》(Inside Llewyn Davis)中,编剧兼导演乔尔?科恩(Joel Coen)和伊桑?科恩(Ethan Coen)兄弟俩挥之不去的忧伤情绪转化成了令人难忘的戏剧性场面。我觉得我的评论本应澄清,这部关于流行文化牺牲品的悲歌有一种特别的味道;其中一些部分相当阴郁。奥斯卡?伊萨克(Oscar Isaac)在片中出演一位自暴自弃的民谣乐手,宿命般地献身于他的艺术,他的卓越表演令这部影片极其震撼人心。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

羽毛球、篮球、击剑、柔道、乒乓球、跆拳道、网球、举重、摔跤、室内排球、拳击、曲棍球#(&xYyCk,DE@+,qFq。
就这一点而言,他预计美国投资会回升,“因为投资一直太弱——除非在经济衰退期,我们通常不会看到投资增长低于消费增长”。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 宜华木业与海尔家居达成战略合作
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

1. How to make pancakes
ZnS#k]Z047gSW1juv]
Michael Na表示,尽管韩国已经和中国签署了贸易协议,中国政府仍有足够多的其他方式惩罚韩国政府。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Mr Lam predicts that any recovery in the market will rely on appetite from cash-rich companies from mainland China, with foreign investors restricting their investments to real estate investment trusts or stocks exposed to developers, rather than actual property.
Leading actress Sun Li played Zhou in the drama. Despite her age, Sun, who was born in 1982, still successfully presented a lovely and innocent teenage Zhou in the eyes of many audience members.
域名注册公司GoDaddy的总部设在亚利桑那州斯科茨代尔市,该公司5月份在坦佩开工建设新的全球技术中心。GoDaddy公司已经在大凤凰城地区雇佣了2,600名员工,新工厂预计将增加300多个工作岗位。其他在亚利桑那州扩大规模的公司包括领先的技术保障服务公司 Asurion。这家公司在凤凰城开设了新的技术支持中心,将在今年年底招聘500多个职位。能源供应商Direct Energy今年在亚利桑那州坦佩开设了新的呼叫中心,需要招聘300多名员工。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

当支持者在周一早些时候涌向总督大楼,一人高喊,"今天,新的波多黎各开始了!" 随着其他人的欢呼,包括那些拿着美国国旗的群众。
“…brought his dog.”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The quality of its students makes LBS particularly valued. “Studying among so many talented people has instilled in me the belief that I can actually achieve something on my own,” comments one MBA graduate from the class of 2011.
'It surprised me, but it's a good sign for Tencent getting abroad, because in particular WeChat is a combination of WhatsApp and Instagram, so it's a unique value proposition that is probably pretty good for emerging market consumers,' he said.
n. 大巴,教练;(火车)客车车厢,四轮马车,经济舱

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

《海底总动员2》将于2016年6月17日上映。
The Producer Price Index (PPI), which gauges factory-gate prices and is a major indicator of economic briskness, rose by 6.3% in 2017, compared with a minus 1.4% for 2016, reversing the trend of continual decline since 2012.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 新房质量“强制险”值得探索
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

But economists generally expect the momentum of the recent past to resume and continue once storm distortions abate. The 45 economists who responded to The Wall Street Journal's latest monthly forecasting survey saw the jobless rate falling to 7.8% by next June and 7.5% by the end of 2013. Some say job growth could accelerate from its slow pace. 'I think businesses are going to have to hire,' said Bob Baur, an economist with Principal Global Investors.[qh]
5. 艾玛?斯通
可以这样说美国银行首席执行官布莱恩?莫尼汉这个人:他很会说话。在给股东的信中,莫尼汉特地感谢美国纳税人,正是由于他们,美国银行才获得了450亿美元的不良资产援助资金。他还说自己如今正在金融改革方面同“政策领导人”紧密合作。不过他是否能做好,比如转变美国银行的境遇,就是另外一回事了。虽然美国银行的确在去年12月偿还了援助资金,但是它仍然有数十亿美元的高风险住房与商用房房贷,这也是为什么它要在年度报告中花8000字来讨论风险了。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

科学家指出,这增加了暴雨和洪水的危险,因为气温升高会导致大气层里积聚更多水蒸气。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

中国现代经销商要求赔偿1.35亿美元
近期,对中国经济的担忧拖累了全球金融市场,影响了欧元区和其它许多经济体的前景。这种担心是欧洲央行(ECB)预计将在周四启动新一轮经济刺激的原因之一。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

这会吓走一些人,这些人不了解你更好。
Online registration will end on Oct. 24. The exam will be held on Nov. 27 in major Chinese cities.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: “内忧外患”逼中国陶瓷行业升级
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

无论是电视剧版的《仙剑》,还是原作游戏,都不仅仅是在中国有着大量的粉丝且深受欢迎,在亚洲其他地方也是如此。
你可能希望分享这些文章的人是出于开玩笑,我也是这么想的。但是我们不能:这个分析指出,通过一个近期的BuzzFeed和Ipsos的公众事务民调显示,75%的美国人(84%的共和党人以及71%的民主党人)很容易就被假新闻的标题所欺骗。这是关于真实性调查、理性思维、扎克伯格的自我意识的梦幻一年。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

LBS’s programmes consistently rank highly for the extent to which alumni reach their targets. “I managed to achieve not only the goals I set for myself but to exceed them with the job I secured,” says one 2010 MBA graduate who responded to the FT survey.
赫洛维兹对爱尔兰广播公司RTE表示,他的新邦德形象强烈忠于50年代的邦德。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

But even in a bad economy some jobs are just not worth it. Are there any telltale signs you should be looking for when trying to decide if you throw in the towel? Here are ten signs to look for to determine if it's time to find a new job:

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

以下是五个脱颖而出的、值得在2014年加以关注的初创企业。
根据近日发布的《第13次国际年度住房负担能力调查:2017》显示,这三座城市高居世界最不可购性房屋市场的前三甲。
The tween is a huge star with three million Instagram followers, whose music videos with the popstar Sia have been viewed more than a billion times on YouTube.
Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

If successful, the funding would underline the rapid growth of the sector this year. In April, Lufax raised $500m at a $10bn valuation.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Local-level work experience will advantageous for applicants, with personnel with more than two years of experience at this level given some advantage.
Businesswomen are booming in Asia: The whole region makes a strong showing, from China and Singapore to New Zealand and Thailand. Entrepreneurship is on the rise: see Zhang Xin (No. 50) , Sun Yafang (No. 77) and Solina Chau (No. 80). And Asian region women are showing their political might, from newcomer Park Geun-hye, the South Korean president (No. 11) and Burmese dissident and parliamentarian Aung San Suu Kyi (No. 29) to Australian PM Julia Gillard (No. 28) and Thai Prime Minister Yingluck Shinawatra (No. 31).
Harvard University topped the rankings for the 16th consecutive year, and Stanford University and University of Cambridge remained in second and third place, respectively.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 2016年中国家居行业的五大风向标
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

That was true, too, of “Mad Men” on AMC. which in its seventh season has all but exhausted its characters and its 1960s setting, but is still keeping viewers guessing about the end, which won’t air until next year. “The Sopranos” ended ambiguously. “Breaking Bad,” put an end to Walter White. Now, the next television mystery looming ahead centers on Don Draper’s last moments, dead or alive.
"Everywhere I go business owners are seeing an increase in demand," said Gus Faucher, senior economist at PNC Financial Services. "Businesses will have to raise wages to attract or maintain workers."

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

adj. 易坏的,脆弱的,浅薄的 n. 复写纸,薄纸副本
Bingo! In fewer than 20 words it combined five previous years’ winners, only to say nothing at all. With a heavy heart, I award eBay my overall Golden Flannel Award for 2016.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

McGowan has also hit out at Meryl Streep, saying that it is 'literally impossible' the actress knew nothing of Weinstein's sexual proclivities until last autumn.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The incomes of graduates from universities listed in China's 211, or 985 key university national projects are far ahead of those from ordinary universities, the survey found.
1.摄影:增长了22.3%
“I saw a woman die and I saw the president of the United States refuse to unequivocally condemn the people who killed her.”

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

如果在“消极情感”和“社交抑制”两个维度得分均为10分或10分以上,那么你就是一个有D型人格特征的人。
[pr?s'periti]
The Lost Tomb is an action and adventure TV adaption of a popular online novel by Xu Lei. This is the first seasonal online TV series in China and the novel is scheduled to be dramatized in eight seasons, one season for each year. The first season was released in June of 2015. The novel series of the same name is about several people`s adventure in ancient tombs, and it enjoyed a wide readership since it was released online in 2006. Thus the adapted TV series had been accordingly highly expected by its fans but turned out to be disappointing. Although there were 24,000,000 hits on the web within the first two minutes of its debut, the season was later criticized by the audiences for its weak storyline and poor quality. Some lines of the series even became jokes on the social media.
[temp'tein]

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

7. AT&T
9. “Creed”(Ryan Coogler)

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 智能家居融入生活 享受居住乐趣
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

例如,佳士得给威尼斯艺术家弗朗西斯科·丰泰巴索(Francesco Fontebasso)在18世纪中叶创作的油画《井边的丽贝卡和埃利泽》(Rebecca and Eliezer at the Well)的最低估价为12万英镑。根据Artnet的数据,在1990年的拍卖会上,这幅令人愉快的洛可可装饰风格的油画是以28.6万英镑购得的。在12月8日的拍卖会上,它仅得到一个电话出价——11.5万英镑(不含佣金),约合17万美元。而投资者们可不认为在购买沃霍尔(Warhol)或巴斯奎特(Basquiat)的作品25年之后会损失约40%。如果一幅早期绘画大师的作品被搁置在交易商的画廊里,想转卖它就更加困难。
The new data released yesterday represent the first snapshot of global trade for 2015. But the figures also come amid growing concerns that 2016 is already shaping up to be more fraught with dangers for the global economy than previously expected.
"You're part of the past, but now you're the future," Lana Del Rey sings on Lust for Life's opening track, "Love".

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

死亡可能隐藏在评论人的十大清单这一仪式之后,也包括实体媒体的死亡:清单在手机上更容易读,就算娱乐媒体的泛滥,已经令深刻的阅读近乎不可能实现。截止到年底,纽约今年一共上映了900多部电影,很多影片都在影院内匆匆来去,由于缺乏观众而被遗忘。尽管如此,这一年里,我看了几百部影片,喜欢其中的一部分;不出所料,大制片公司和独立公司都有垃圾制作,但和往常一样,也不乏有价值的作品。下面是我在2015年最喜欢的影片,以及今年的十则杂记。
今年获得奥斯卡提名的音乐人将会齐聚一堂登上奥斯卡颁奖典礼的舞台。

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