Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Autonomous cars: Researchers are working on devices that will automatically park your car in a parking lot without you being in, or near, the car. It will also slip a note under the wipers of the car next to it with your phone number and insurance carrier in case of any scratches.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
8. Julia Roberts - $12 million
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
I am afraid to go out in the sun now because of the holes in the ozone. I am afraid to breathe the air because I don't know what chemicals are in it. 我现在害怕晒太阳，因为臭氧层出现了空洞。我现在害怕呼吸空气，因为我不知道那里有多少化学物质。
菲律宾参议院一委员会就国内发生的法外处决事件举行了听证会，罗纳德?德拉罗萨(Ronald Dela Rosa)在会上表示，自7月1日杜特尔特就任总统后，有712人在警方缉毒行动中被杀，还有1067起死亡正被作为与毒品相关的自告奋勇者杀人案件在调查中。
Over at Huffington Post Mark Gongloff warns: That 'dramatic downgrade of U.S. economic growth in the first quarter revealed the economy's lingering weakness, exposed the folly of Washington's austerity obsession and slapped the Federal Reserve's newfound optimism right in the face.' And with politics deteriorating, it'll get worse.
Trends and targets in antiviral phototherapy
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
For all of the acceptance speech kerfuffle when Gwyneth Paltrow won best actress for her role as Viola de Lesseps in John Madden’s 1998 film Shakespeare in Love, the Hollywood star has since said she keeps the award tucked away – “the thing freaks me out”.
4. Am I eating healthy? The types of foods we eat can greatly affect how we feel both physically and emotionally. Eating too much junk food can lead to crankiness and a relatively low energy level, whereas eating healthy foods can lead to better moods and a more positive energy level.
Diagnostic technologies for COVID-19: a review
Golden State Warriors point guard Stephen Curry said he has visited China every year since 2013 and the fans there are incredibly supportive.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
The nearest star, Proxima Centauri, has a planet orbiting it not much bigger than Earth. Its "year" is only 11 days. But it's in the habitable zone because Proxima Centauri is a red dwarf star about 100 times fainter than the sun. And there's hot news that a similar star, 40 light years away, may have three planets in its habitable zone.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
《出生于缅甸皇室的她成为军阀和大毒枭》(The Female Warlord Who Had C.I.A. Connections and Opium Routes)
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
What would he try for his solo move: "Sweet Creature" and "Ever Since New York" are intimate acoustic ballads; while "Kiwi" lets him strut his Oasis-style self at top volume. "Two Ghosts" is a break-up lament .
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
John Stevenage, chief executive of British Mensa, said he was delighted for Nishi. He said: 'I hope she will make full use of her membership to meet new, like-minded people and challenge herself. Joining Mensa opens the door to an international network of more than 100,000 people and many members make friends for life.
Antiviral drug discovery: broad-spectrum drugs from nature
Influenza neuraminidase: A druggable target for natural products
Steven Spielberg directs Meryl Streep and Tom Hanks in The Post, a thrilling drama about the unlikely partnership between The Washington Post's Katharine Graham (Streep), the first female publisher of a major American newspaper, and editor Ben Bradlee (Hanks), as they race to catch up with The New York Times to expose a massive cover-up of government secrets that spanned three decades and four U.S. Presidents. The two must overcome their differences as they risk their careers - and their very freedom - to help bring long-buried truths to light.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The overall 2018 ranking encompasses more schools than ever before – 1,250 universities located across 74 countries. This is an increase from the 1,000 schools in 65 countries included in last year's edition.
Dua Lipa, 'Dua Lipa'
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
6. Our last universal common ancestor gets a makeover
Bernard Baumohl, chief global economist of the Economic Outlook Group, said he is even more optimistic. "The next two years could be the best two we have seen in at least a decade," he said. "There is clearly a lot of evidence the economy is gaining a lot of momentum."
The maker of Post-it notes and Scotch tape authorized a $12 billion stock repurchase program in February, replacing its current $7.5 buyback program. 3M's (MMM, Fortune 500) move followed its announcement late last year that it intends to spend $10 billion on acquisitions and repurchase up to $22 billion of shares over the next four years.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
"They say: 'I wonder why she kept her head down in the meeting; I wonder why she's not eager to take over that project; I wonder why she's leaving early a couple days a week," Kay says. "You're planting questions in their head."
岁末来临，二十多部影片轮番上映(hit cinema)。而今年的贺岁片大战随着《龙门飞甲》和《金陵十三钗》的上映而硝烟四起，一场票房PK战也随之拉开帷幕！December is a golde
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
scary puppy like head tilts and glares
8. Pour-Protection by Pet Life
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Boston Consulting Group could also be poised to make a change given its managing partner, Richard Lesser, is due to come to the end of his second term in October. His future is unclear, however, as the firm declined to comment on its election process or how many terms its leader can serve.
It was the best of times, it was the worst of times…
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
By 2020, annual box office sales are expected to reach 100 billion yuan, according to industry estimates.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
He argues, however, that “US monetary policy is often just as important as domestic factors in explaining the incidence of EM crises, if not more important.”
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Where Goods Made From Trafficked Wildlife Go
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
在牵手其他领域的精英这一点上，谷歌并非独家。今年早些时候，英特尔（Intel）便宣布与美国时尚设计师协会（Council of Fashion Designers of America，CFDA）和奢侈品零售商Opening Ceremony合作，设计智能手镯。时尚品牌汤丽柏琦（Tory Burch）也与Fitbit携手设计了与可穿戴技术创业公司Misfit Wearables的无线运动跟踪器Shine Tracker类似的吊坠与手镯。而苹果（Apple）也发掘了各行各业的人才，包括博柏利（Burberry）前任首席执行官安吉拉o阿伦德茨（担任零售主管）、伊夫o圣o洛朗（Yves Saint Laurent）前任首席执行官保罗o丹尼佛以及耐克（Nike）的前任设计主管本o谢弗。
Celebritites always seem to have a better life than the rest of us;nicer house,cooler cars and even cuter children.Just look at these pictures of Shiloh Jolie-
People on both sides of the Taiwan Strait are brothers and sisters, and no matter how the situation on the island evolves, the mainland is determined to maintain Cross-Strait stability.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
We learned about the causes and consequences of rising obesity around the world.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Tsinghua University and Peking University are ranked in 14th and 17th place respectively -- the same positions they held in last year's rankings.
Demagogues are the Achilles heel of democracy.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
However, 2016 saw the rise of Chinese mobile phone-makers. Huawei shipments grew 30.2 percent year on year to 139.3 million units, and the company retained its No. 3 position globally.
There is still tremendous untapped potential in China-Russia economic and trade ties and the two economies are highly complementary. The goals set for the two-way trade can be achieved.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Temperatures in 2015 also shattered the previous record set in 2014 by 0.13C, according to Nasa.
When you think of him, your heart would jump between fast and fast.
In addition to meeting quality standards, imported products must be correctly labeled in Chinese, according to national regulations.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Major areas of work for 2017
"Students are not suited for starting businesses on their own," said Zhang, adding that vocational students are more eager to start businesses than university undergraduates.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Negative emotions such as worrying, stress, depression and anger visit type D personalities more often. A small event that is usually overlooked by others can bother a type D a lot and even ruin his mood.
It's impossible to list every woman who's ever existed, this list obviously be restricted to women who've achieved a fair level of celebrity. These are the hottest women celebrities of 2015.
5.Create a Study Space
A modular microarray imaging system for highly specific COVID-19 antibody testing
'A little bit in shock,' said director Steve McQueen, before shrugging 'Roll, Jordan, roll'-the lyrics to the old gospel song sung in the slavery epic.
"The rate of college students who have had sexual experiences using condoms is less than 40 percent," said Han Mengjie, director of Chinese Center for Disease Control and Prevention.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Despite car and truck sales that motored past 16 million for the first time since 2007, recalls dominated the news for most of the year. General Motors GM 1.42% held center stage, dealing with cascading revelations about faulty ignition switches and recalling millions of vehicles. While GM opted for something approaching full disclosure of its missteps , publishing an report into company-wide fumbles, Japanese airbag maker Tanaka chose to stonewall. It left any remedies up to its beleaguered customers, notably Honda and Toyota. They are the ones who deal with the fallout of exploding safety devices that fatally fired shrapnel throughout the passenger compartment.
Reality Competition Program: “The Voice” (NBC)
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
An investigation is continuing into how La La Land was wrongly named Best Picture rather than the triumphant Moonlight.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
外部事件的影响。《消费者报告》（Consumer Reports）杂志曾经对Model S大加吹捧，但最近该杂志也报道了它的一些常见故障，包括门把手失效，中控触屏白屏，导致车内大部分功能不能使用等等。汽车网站Edmunds.com也找了Model S的麻烦。更多此类报告无疑会影响特斯拉到目前为止非常正面的声誉。
Metals cases made up a record 46 per cent of the 233 anti-dumping actions brought worldwide in 2015, with the steel industry accounting for almost all of the metals complaints.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
If all this comes to pass, Huberty estimates that Apple's addressable smartphone market in China, which had dwindled to 10%, could triple to nearly 30%.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
52% of the world lived in extreme poverty in 1981. This number dropped down by 21% in 2010, as 721 million fewer people no longer live in absolute poverty.
"I don't know what happened," Lowry said. "I just know I got a call for offensive foul. It happens. It's the NBA. That's all I can say about it."
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Three of former US president Barack Obama's tweets were among Twitter's list of 10 most retweeted this year, while none of current US President Donald Trump's tweets made the list.
'In the meantime, the U.S. continues to grow its own domestic production both in oil and gas. I think, for us, it's less about where the actual price is going--it's more about how much more growth is left in North American oil sands, shale gas, shale oil,' as well as shale exploration elsewhere, he said.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
At Japan Expo, we are very honored to interview Gen Urobuchi and also begraced with the presence of Nitro+ president Takaki Kosaka.Let's begin.Translated by Emmanuel Bochew.
4. We were wrong - the testes are connected to the immune system after all. Researchers have discovered a "very small door" that allows the testes to send one-way signals to the immune system, and it could explain why some men struggle with infertility, and why certain cancer vaccines keep failing.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Today's and tomorrow's technology sits on top of multiple layers, every one of which is changing and has to inter-operate with others. This makes our gadgets, the internet of things, phones and laptops unstable. And it makes consumers irritated. How many of your apps actually work--and actually make life easier, faster or more fun? I'd expect to see consumer cynicism grow, as delight is overtaken by disappointment. This will put pressure on hardware and software developers to deliver that most boring of qualities: reliability.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Every employee wants a pat on the back once in a while, and the best bosses understand the importance of recognizing and appreciating employee contributions. This doesn’t have to mean bonuses or fancy corporate awards, but regular and meaningful expressions of appreciation。
Length-scale dependence of protein hydration-shell density
The University of St Gallen’s domination of the Financial Times’ ranking of masters in management courses continues for another year.
But there remains a mass of old master paintings in dealers’ stocks — and in collectors’ minds — whose asking prices still hark back to the age of Tommy Cooper. Unfortunately, in today’s market, and at those prices, many of these paintings will be as sellable as that Stradivarius canvas with the hole in it.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
4. “Carol” This is the first movie that Todd Haynes directed that doesn’t have his name on it as a writer. Working from Phyllis Nagy’s distillation of the Patricia Highsmith novel, he reaffirmed that filmmakers don’t need to generate their own screenplays to be great, a truth many aspiring and established auteurs disregard.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
They expect the heat to get much worse over coming decades, but already it is killing forests around the world, driving plants and animals to extinction, melting land ice and causing the seas to rise at an accelerating pace.
Leading the pack of the best airlines for holiday travel is Hawaiian Airlines, followed by another Pacific Coast-focused carrier, Alaska Airlines. Conversely, the worst airline for holiday travel is New York-based JetBlue Airways, with ExpressJet, a regional carrier, coming in next to last, according to the FlightAware data.
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