Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
The total amount of remittances, which is estimated to reach $450 billion in 2017, has risen by more than 50 percent in the past decade, IFAD said.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”
Those quickly sold out, locking out the vast majority of fans in soccer-mad Brazil.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
?The Aston Martin doesn't hurt. Not at all. Neither does dropping tons of cash at exotic casinos -- throwing money around makes men more attractive to women who are interested in flings. And, like Bond, men who gamble with women around are better at it.
China becomes the first middle-income country to join the ranks of the world's 25 most-innovative economies, according to the Global Innovation Index (GII) released last Monday.
Sometimes bosses suck. But if your boss sucks all the time and takes advantage of your time, it's time to find a new job.
Trends and targets in antiviral phototherapy
During a town hall hosted by MSNBC on last Monday night, host Rachel Maddow asked Clinton whether she would match a campaign promise Canadian Prime Minister Justin Trudeau made good on earlier this year.
6. Cutting Down on Saturated Fats Could Preserve Your Memory
Equally, a three-week interning stint at PwC in the school summer holidays gave her the chance to sample life in a professional services firm. “I didn’t think I would get a place on [PwC’s programme] as I had no business experience,” she says.
Accounting and finance grads will be in demand too, the poll says. Note to college students already looking ahead to the summer: 52% of employers in the survey said they prefer to hire graduates with internship experience.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
“He’s informal, candid and approachable,” says Ginni Rometty, chief executive of IBM, who praises him as “very authentic. It’s the hallmark of a modern CEO. What you see is what you get.”
ACE2 as a potential therapeutic target for pandemic COVID-19
Anyway, it's nice to see that LeBron has filled into his monster physique nicely in the past nine years.
In a working paper published on Tuesday, Robin Koepke, economist at the Institute of International Finance, an industry group, argues that investors, EM policymakers and the Fed itself have neglected the role of US interest rates in provoking currency, banking and debt crises in the emerging world.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Obama watched the returns on television at his Chicago home. Senior campaign strategist David Axelrod said via email that he was feeling "great."
While Insead’s joint programme dropped back into second place, its single-school programme moved up three places to fourth, a place it last occupied in 2011.
LBS’s programmes consistently rank highly for the extent to which alumni reach their targets. “I managed to achieve not only the goals I set for myself but to exceed them with the job I secured,” says one 2010 MBA graduate who responded to the FT survey.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Company: (Wonderbag) Natural Balance
When he was offered the role of "Will" on Fresh Prince, he had 70% of his wages garnished for the first three seasons. After three years, he was able to take home his full salary. Basically, the first line of the theme song could have been written about Will Smith's real life: "This is a story all about how/My life got flip-turned upside down." Except in real life, the "guys making trouble in his neighborhood" was the IRS.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Never accept the job immediately. Say you need to think about it overnight. Once you sign on the dotted line there's no room for negotiation.
Antiviral drug discovery: broad-spectrum drugs from nature
n. 史诗，叙事诗 adj. 史诗的，叙事诗的，宏大的，
Rihanna, who came in at second place, earned her runner-up position "following another 12-month period in which she was absolutely bloody everywhere and yet we all entirely failed to get sick of her," per FHM.
Influenza neuraminidase: A druggable target for natural products
According to BusinessInsider.com, 'embracing hyperbole, ' Faber 'suggested that QE would basically be a part of everyday life for the rest of our lives, ' adding that back in 2010 in the early days of Bernanke's disastrous experiment, Faber warned 'the Fed's headed for QE99.'
Civil War takes place after the events of Avengers: Age of Ultron, when the government decides that the Avengers should work under them and not on their own. Steve Rogers, aka Captain America, is against this idea whereas Tony Stark, aka Iron Man, is with the government. This leads to a conflict between Captain America and Iron Man.
Best chance: If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
By the time of the Asian crisis of 1997-98, he says, the Fed had become more responsive and pulled back from its tightening cycle on concern that the turmoil in Southeast Asia would affect the US economy.
The central government has allocated a special fund of 100 billion yuan to provide assistance to workers laid off from overcapacity cuts, and also has asked local governments to set up matching funds.
The role of biosensors in the detection of emerging infectious diseases
1)Thank You: Common courtesy? Sure. But tell me this: When was the last time you forgot (or rejected) gratitude? Whether given in private or public, a sincere ‘thanks’ creates goodwill. Don’t forget your mother’s advice: “Say please.” People are always happier doing a favor than taking an order.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Whiteness means being part of the group whose appearance, traditions, religion and even food are the default norm. It’s being a person who, by unspoken rules, was long entitled as part of “us” instead of “them.”
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
v. 构成，把 ...
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The latest commerce ministry figures do not include real estate purchases by individuals, many of whom exploit loopholes in China's capital control regime to obtain foreign currency. But the foreign exchange regulator has recently moved to close such loopholes, notably by tightening control of forex purchases by individuals, who are allowed to exchange $50,000 worth of renminbi for foreign currency each year.
Mark Williams, chief Asia economist at Capital Economics, adds: “We expect that the performance of EM exports will continue to improve in 2017, with export values rising modestly in year-on-year terms.”
He then proceeded to ram the violin through the canvas.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
In January, Wal-Mart (WMT, Fortune 500) U.S. president And CEO Bill Simon pledged that the world's largest retailer would hire 100,000 veterans over the next five years. In addition, the biggest private employer in the U.S. said it would offer employment to any honorably discharged veteran within his or her first 12 months off active duty.
从“高跟鞋门”到“金棕榈狗狗奖”（Palm Dog），再到迅速走红的“老爹身材（Dad bod）”，戛纳电影展的这12天，真是令人眼花缭乱。随着电影节进入尾声，英国广播公司回顾了本届戛纳影展上的九桩事。
Glazer surely took something, again, from Kubrick, especially in the scene in which his alien is born in some dimensionless otherworld. He took something from Nic Roeg and The Man Who Fell to Earth and a little, perhaps, from David Lynch – of which, more in a moment. But alongside the sci-fi exoticism he brought the grit and sinew of contemporary realism, calling to mind the work of film-makers like Ken Loach, or even Abbas Kiarostami and the opening of his The Taste of Cherry, in which a desperately unhappy man drives around the itinerant labour markets of Teheran looking for someone to help him. These fantastic alien forms are scuffed with ordinariness and even bathos. The scene in which the alien uncomprehendingly watches Tommy Cooper on television is a masterpiece of tonal suspense.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
vt. 编预算，为 ... 做预算
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Crucially, they note, instability and conflict around the world could continue to drive inflation and affect the costs of living within certain cities.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
"Why do the slaves all dress in white and look like fairies in this drama? Plus they even ran faster than horses. Is it reasonable?" user Shiweitian said.
It was the best of times, it was the worst of times…
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
The application window will close on Saturday, and successful candidates must pass the 2016 national civil service exam, which starts on Nov 29, before they're granted a job interview in March.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A report from the ministry showed that employers recruited 5.2 million workers through public employment service agencies in the first quarter, dropping 229,000, or 4.5 percent, from the previous year.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
如果这个目标真的能够实现，届时特斯拉的规模将超过林肯（Lincoln）和保时捷（Porsche）等豪车品牌的美国分支。这两个老字号豪车品牌都有更多样化的产品阵容、长期的经销商网络、成熟的营销和广告策略。特斯拉如果真的能卖出预期的数字，那么其销量的半数将来自现有的Model S轿车，其它一半则来自明年年初才会量产的Model X七座跨界车。
But perhaps we are finally there. Perhaps the curtain had to fall on the show before it could fall on that part of the ready-to-wear shows. Perhaps the history hamster wheel that we seem to be on — which has seen us cycle through the 1970s as well as some of the big hair and bigger shoulder pads of the 1980s (yes, we are there again) — will finally stop turning.
Then why do you go out and do the things you tell us not to do? 你们大人为什么去做与你们教导孩子相反的事情呢？
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Chicago-based rival AT Kearney is also preparing for a change at the top, with a vote to replace Johan Aurik, who has already served the maximum two terms as managing partner, due to take place in the first quarter of 2018. His replacement will be expected to focus on how to pull AT Kearney out of the ranks of mid-sized players.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
The United States saw its real GDP increase at an annual rate of 3.9 per cent in the three months ended September,according to official data released last month.
Yet that's finally about to change. With hiring up and unemployment falling, businesses will have to go the extra mile for employees or risk losing sales to competitors because they lack enough staff to boost production.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Bond King Bill Gross admits, 'QE must end.' Trillions of cheap money 'has distorted incentives and inflated asset prices to artificial levels.' But now Gross says 'the Fed plan may be too hasty.'
smiles and puma snarls
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
What? Hasn't his firm made enough money off Bernanke's cheap money printing? So he's blaming 'lower growth on fiscal austerity, ' even as Bernanke keeps blowing up the Fed's balance-sheet bubble by trillions under the delusion he's America's savior because our dysfunctional Congress failed?
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
If he wins the primary, he would face off against first-term Republican Gov. Phil Scott, 59.
The World Health Organization this year declared H1N1 a global epidemic. Fortunately, it is much less threatening than people previously believed, and newly introduced vaccines seem to have quelled lingering fears.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Wishing you all the blessings of a beautiful New Year season.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
I do not see much evidence that radical “managerless” models such as “Holacracy” will catch on. But more companies will realise that if they constantly test innovative ways forward — as start-ups do — they will be more flexible and decisive than old-style bureaucracies and meritocracies.
Ms Rogers added that she had not given her son parental consent to play the game as stated in its terms and conditions, and that as the game was free to play, the studio could not claim loss of profit as a result of the cheats.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
“The Man Who Knew is an impressive work of scholarship,” Lionel Barber, editor of the FT and chair of the book award judges, said. “It’s a masterpiece of political economy and, above all, it’s a great and enjoyable read.”
I did not create the characters inAldnoah. I made the mainframe of the story until the preliminary version. Butin fact Inaho's character is different than what I wrote. I don't really have aconnection with this character, so this is an exception.
Those quickly sold out, locking out the vast majority of fans in soccer-mad Brazil.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
We will boost the development of modern agriculture.
Benchmark oil prices dropped below $40 a barrel last week, the lowest level in six years, darkening investor sentiment towards commodity-linked companies and exporting countries including Brazil, Russia and South Africa.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
斯德哥尔摩经济学院(Stockholm School of Economics)是今年排行榜上的大赢家，该学校的排名攀升16个位次，排在第28位，不仅排名晋升速度为年度最快，而且扭转了去年排名下滑11位的局面。
10. Are YOU Re-Energized?
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Anton, who works in the military, said: 'I thought the Beyonce routine was inappropriate when Steph first told me about it, but when I saw her on the stage doing it, it worked out quite well and everyone enjoyed it.'
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Chinese insurers saw their profits implode in the first six months of 2016.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Company: The Grommet
Best Luxury Brand: Porsche
A facile assay for rapid detection of COVID-19 antibodies
James Franco’s new movie about the making of The Room will make you belly-laugh, but its comedy is also deeper and richer than mere mockery.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
These documentaries use the standard tools — archival footage, talking-head interviews, carefully selected musical cues — to write history in the present tense. In the era of Black Lives Matter, the stories of the Black Panthers and the jazz singer and activist Nina Simone could hardly be more relevant. Mr. Nelson and Ms. Garbus tell them beautifully.
Now that Chris and his girlfriend, Rose, have reached the meet-the-parents milestone of dating, she invites him for a weekend getaway upstate with Missy and Dean. At first, Chris reads the family's overly accommodating behavior as nervous attempts to deal with their daughter's interracial relationship, but as the weekend progresses, a series of increasingly disturbing discoveries lead him to a truth that he never could have imagined.
7. Smart cookie oven
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
在根据真实罪案改编的电影《狐狸猎手》(Foxcatcher)中，以出演喜剧闻名的演员史蒂夫·卡瑞尔(Steve Carell)饰演大富翁约翰·E·杜邦(John E. du Pont)时隐藏在假面具后面。这个造型最突出的就是鸟嘴状鼻子。
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Finance and real estate made up the backbone of home-grown brands, with 38 and 23 companies coming into the list respectively, and accounting for 30 percent of the brands on the list.
‘The Mindy Project’ It doesn’t matter that Mindy Kaling’s comedy on Fox is in its third season and still not a hit, because it keeps improving with age. It has grown from a one-comedian showcase into a very funny ensemble effort, thanks in part to the addition of Adam Pally in Season 2 and jokes about Ms. Kaling’s alma mater, Dartmouth.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Hope you enjoy the happiness of New Year and all the trimmings.
Airlines with operations based west of the Rockies boast the fewest flights that arrive late during the holidays, according to data compiled for Forbes.com by FlightAware.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Length-scale dependence of protein hydration-shell density
Beijing is looking to unload excess reserves built up under the government’s subsidy policy.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
NBS senior statistician Sheng Guoqing attributed the slowdown mainly due to a 1.4-percent decline in food prices, which were down for the first time in 15 years.
The joint programme delivered by IQS of Spain, Fu Jen Catholic University in Taiwan and the University of San Francisco saw the biggest rise. Its Master in Global Entrepreneurship Management jumps 34 places to 43rd, making up for a drop of 19 places the previous year. The only programme to be delivered on three continents, it is ranked top for international course experience.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
在导演阿方索?卡隆(Alfonso Cuaron)和同事们（其中包括知名电影摄影师艾曼努尔?卢贝兹基(Emmanuel Lubezki)、制片设计师安迪?尼克尔森(Andy Nicholson)和编剧霍纳斯?卡隆(Jonas Cuaron)）的共同努力下，《地心引力》丰富了电影的拍摄手法。《美国电影摄影师》(American Cinematographer)杂志上个月的封面故事刊载了关于《地心引力》制作过程的文章，对电影技术感兴趣的读者可以一探究竟。读者们可以在网上阅读该杂志。不过任何看过《地心引力》的观众都已经领会到了该片的情感内涵，这部电影把观众们带进入了一个寂静危险的外太空和一个深度愉悦的内心世界。
会。梅亚德是执政党革命制度党(PRI)的候选人。他主要的竞争对手是强硬的左翼领导人安德烈斯曼努埃尔洛佩斯奥夫拉多尔(Andrés Manuel López Obrador)——可以感召人群的激情演说家。梅亚德需要克服很多问题：在去年1月一夜间把油价上调20%、引发通胀飙升后，他必须说服选民自己仍然是可以信任的。他还必须证明自己是个有主见的人，而不仅仅是这届不受欢迎的政府的傀儡——在遏制猖獗的腐败和犯罪行为方面，这届政府极为失败。但是凭借强大的PRI拉票机器，他可能势不可挡。在墨西哥只有一轮选举的体制下，30%的选票可能就足以让他当选总统了。
About this collection
His footballing rival Lionel Messi - who the 31-year-old beat to be crowned the World Player of the Year in January - was second on the list, taking home pound 56 million in 2015/16.