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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Marco Montanari, the head of passive asset management for Asia-Pacific at Deutsche AM, agrees that fundamental changes to distribution must be made before the Asian ETF market can move to the next level.
愿你的新年充满温馨,祥和,与亲人团聚的快乐,祝乐陶陶,新年乐无限。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Domestically, an increasingly active middle class is generating pressure for more accountable governance. Mounting inequalities have nurtured a sense of injustice; 200m migrant workers remain second-class citizens and corruption is worsening. Tackling these problems is urgent, but China's economic successes have fostered an unwarranted self-confidence. Instead, motivated by the Arab spring, the system has moved aggressively to contain any social discontent that might spark more politically sensitive movements.
n. [宗

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

为保证更快的经济增长就必须要要消除美联储所担忧的另一个恶魔:通货紧缩,或者说价格下降。Baumohl 称“经济增长达到3%以上,并且自90年代以来新增了大量工作的国家发生通货紧缩几乎是不可能的”。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

相比之下,十年前名列榜单前20的城市中有6个亚洲城市、10个欧洲城市和4个美国城市。这项调查计算了93个国家的131个城市的生活成本,研究结果用于企业计算转移员工的成本。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

channel
谢丽尔·布恩·艾萨克斯,学院理事会主席
以下是根据官方数据(所有收入均按市场汇率折合成了美元)得出的世界主要国家领导人收入排行。
一切始于比蒂打开信封准备念出最佳影片得主的那刻,他看上去很困惑,停顿了很长时间,然后望向唐纳薇。“来吧!”比蒂把信封交给唐纳薇,后者宣布道:“《爱乐之城》!”

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

The THE Asia University Rankings for 2017 rated Peking University and Tsinghua University, both in the Chinese capital of Beijing, as the second and third best universities in the continent. National University of Singapore is ranked the best.
净利差——即贷款和存款的利率之差——在降低,因为中国撤销了对存款利率的剩余管制。2015年,中国银行业平均利差下降约46个基点,至2.54%。
Celebrity Latin tattoos may be fuelling a revival of the ancient language in schools, it emerged today。  明星们的拉丁语纹身引发了一阵学习拉丁语的热潮。
Erle Spratt, who manages M&G’s Asia property fund, an open-ended investment vehicle, says it is risky to invest directly because assets are not easy to find and price. “It is a very difficult market to buy assets in for investors like us, because developers have very substantial holdings and they tend not to sell,” he says.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Other Chinese companies that filed a large number of patents included ZTE, Alibaba, Xiaomi, BYD and Haier, all of which are rapidly expanding into Europe.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

syndrome

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

9.《老友记》中卡罗尔和苏珊的婚礼
中国国产3D奇幻/冒险片《捉妖记》2015年7月在国内上映后打破一系列票房纪录,成为2015年中国内地最卖座的电影

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Meanwhile, a salesman from online travel company Tuniu Corp told the Financial Times that it had on Friday “removed all tours to South Korea due to the Thaad issue”. A search for South Korean tours on the website returns the message: “Sorry, we have not found a relevant product.”
Not every band can sound fresh 40 years into a career, but not every band is Blondie.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Will the Saudi Aramco public offering debut on an international market
施密特在接受采访时问道,“为什么我们接连看到如此多的创纪录温暖年度?这是因为地球正在变暖。根本的问题是,这是一种长期趋势,这种趋势不会消失。”

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

“我们从斯雷布雷尼察大屠杀事件了解了荷兰和荷兰人是什么样的,”埃尔多安说起现代荷兰历史上最可耻的一幕,“我们从他们屠杀那里的8000名波斯尼亚人就知道,他们品德败坏到何等地步。”
[m?s]
However they went ahead with plans to send 100,000 anti-Pyongyang leaflets.
在叙利亚问题上,普京说,俄罗斯将继续开展军事行动,直至政治进程启动。他说,必须让叙利亚人民自己决定由谁来治理这个国家。他还说,他不知道俄罗斯是否需要在叙利亚设立永久军事基地。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

[m?:'t?liti]

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 网站不能随意发布房源
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Cousins's deal qualifies as a blockbuster, the Raptors made two strong moves to bolster their contender status, and the race for the West's last playoff spot got far more intriguing, among other storylines.
LeBron James

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

这部电影是完全的、纯粹的流行天堂,其中不乏独创性和黑色幽默。动作编排恰到好处。某些画面,观影者忍不住想冲出电影院叫来朋友观看。但你并不敢离开位置,你怕错过这绝妙的片段。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

制造业PMI降至5个月以来的最低水平,是由于受访企业表示,更严格的环保政策限制了业务扩张。这些政策旨在遏制每年冬天笼罩中国大部分地区的有毒烟雾。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 北京积分落户申报仅剩两天
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

"We're excited to have these talented artists showcase the powerful contribution music makes to filmmaking," the show's producers Michael De Luca and Jennifer Todd announced in a statement on Friday. "It's a privilege to welcome them to the 90th Oscars stage."
associate
2. 邻客音(LinkedIn)。品牌喜爱度:47%/排名:309
“One employee’s parents contacted the company to let us know their son was resigning.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

多年来,西方排放量的缓慢减少,被东方排放量的日益增加所抵消。2013年,这种趋势仍在继续。中国的排放量增加了4.2%,印度增加了5.1%。中印两国一直在以极快的速度修建火力发电厂。
According to exam questions and some test-takers' feedback posted online after the exam, the difficulty of the questions was moderate and hot political and social issues, such as the Long March rockets, China's foreign affairs, the Yutu lunar rover and entrepreneurial efforts by college students, were mentioned.
我们必须牢牢抓住就业这一民生之本,让人们在劳动中创造财富,在奋斗中实现人生价值。
它被广泛误解为一部关于小说家大卫·福斯特·华莱士(David Foster Wallace)的传记电影,其实庞索特的这部影片是一部关于新闻的坏方法的喜剧,以及对文学名誉机制充满了解的辛酸讽刺。杰西·艾森伯格(Jesse Eisenberg)与杰森·西格尔(Jason Segel)使用“男人老友电影”(buddy movie)的传统方式,完美地呈现出一个新的子类:亦敌亦友电影。
只有两个人知道奥斯卡奖获奖名单,他们负责审计整个流程,这两个人就是PwC公司的税务顾问玛莎?瑞兹和会计师布莱恩?卡利南。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

After working for half a year, the average monthly income for 2014 graduates is RMB3,487, a significant increase from RMB3,250 in 2013 and RMB3,048 in 2012.
鉴于《速度与激情7》定于2014年夏季在各大院线上映,“巨石强森”将再次迎来丰硕的一年。凭借影片《海格力斯》(Hercules)他还可以做得更好。该片讲述的是这位神话英雄在完成其著名的12件苦差后的生活,极有可能拍摄续集。如果该部影片也能取得巨大成功,那么约翰逊在2014年将获得丰厚的票房收入。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The dumbest 'smart' objects of 2016

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

日前,斯坦福大学商学院(Stanford Graduate School of Business)教授彼得o库迪斯基于这场荷兰危机共同撰写了一篇文章,围绕“个人经验(而非市场信息)决定乐观、悲观以及信贷的获得与否”这种不那么科学的方法给出了现代经验。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 2016或是家具行业的品牌觉醒年
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

在经历了长达几十年的许诺后,新的基因疗法终于开始有了一些真实的好成果。不过就像所有的新型疗法一样,基因疗法需要向公众准确地传递如何治疗以及治疗背后的原理,这和疗法本身一样具有挑战性。
“He is very, very good at not allowing that pressure to in any way disrupt what Apple is trying to achieve,” says Mr Iger. “Clearly there were issues that were on his mind but Tim made sure they were never on the minds of the people who do what Apple does best.”
Stand: Wal-Mart U.S. President and CEO Bill Simon pledged to hire veterans
教育部也已采取了一些措施,例如取消考试成绩、将作弊行为记入个人档案中。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

有7所商学院在过去一两年落榜后重新上榜。
在1991年至2010年之间,癌症死亡率显著下降了20%,这比过去十年下降总和的10%还要多。总有一天,我们会跟癌症说再见。
2016年空前的海外收购潮消耗了中国大量外汇储备,随后监管部门开始严格限制境外交易。今年8月,中国政府出台了新框架,鼓励那些符合北京战略重点的交易,并限制涉及娱乐、体育和豪宅等方面的交易。
蕾哈娜在榜单上排名第二,获得亚军,《男人装》表示:在这12个月以来,她真是无处不在,但是我们依然没有对她审美疲劳。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

我在喜马拉雅山的山脚下度过了青春岁月,当时有个朋友被我们称为“追梦人”。他每天都在享受最微妙的乐趣——用五颜六色标注蝴蝶、数地平线上的高峰,对着形状各异的云朵编故事。他是个快乐的家伙,对生活的美妙深有体会,容易兴奋激动。亲爱的2013届毕业生,我认识这家伙很多年了,今天我坐下来给你们写这篇文章的时候,突然想到了他。
For: A huge box office hit that could benefit from a slowly-changing Oscar voting demographic.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

And regarding Ukraine, the Russian president again denied that there are Russian troops operating inside eastern Ukraine where a pro-Russian separatist movement is fighting Ukrainian government troops. But he said Moscow never denied that "certain people" were there carrying out tasks "in the military sphere." He said Russia plans no sanctions against Ukraine, but will not extend preferential trade to Kyiv.
2016年,9个省级地区的GDP超过3万亿元,比上一年增加3个;25个省级地区的GDP突破1万亿元,与上一年持平。
坚决打好蓝天保卫战。
2.这里没有人能够回答你问的任何关于击剑的问题。还是去google一下吧。
长话短说,1772年圣诞节后,Seppenwolde很快就破产了。这场灾难是当时荷兰报纸的头条新闻。它彻底毁了阿姆斯特丹一批商人和银行家。为了防止出现全面的信贷崩溃,阿姆斯特丹市只能作为最后贷款人暂时介入。这种情形是不是似曾相识?

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

“有个员工烤了个蛋糕,把辞职信直接写在了蛋糕上。”
China will not see nor allow massive unemployment of particular groups this year, as the government is capable of ensuring a favorable environment to generate jobs.
Length of program: 24 months

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Prince Miteb, who headed the powerful National Guard until early November, was released on November 28th, the official said. At least three other suspects have also finalized settlement deals.
11) I often feel unhappy 0 1 2 3 4

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

I don't know about you, but if I had a separate calendar for work, school and life, I'd be a complete mess. When everything in your life is on one calendar, in one planner, you can't double-book anything. You know, like an important test and a dinner with your boss.
这些新数据是由一个叫做全球碳计划(Global Carbon Project)的追踪项目提交的,发表在了期刊《自然·地球科学》(Nature Geoscience)上。数据公布之际,正是联合国(United Nations)一次峰会召开前夕。此次峰会意在激发新的政治愿望来解决气候变化问题。科学家说,这些数据表明,如果要把长期的全球变暖问题控制在可以承受的范围内,还需要做出极大的努力。
Mr Hoogewerf said that Mr Wang delisted his group’s property arm from the Hong Kong stock exchange this year in the hope of realising a richer valuation for it on the Shanghai or Shenzhen bourse.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

11. 另外26部我喜爱的影片——为什么不呢?其中很多影片本可以跻身我的十佳之列的。《迷失1971》(’71)、《艾米》(Amy)、《失常》(Anomalisa)、《骇客交锋》(Blackhat)、《芝拉克》(Chi-Raq)、《机械姬》(Ex Machina)、《实验者》(Experimenter)、《诉讼》(Gett: The Trial of Viviane Amsalem)、《恐龙当家》(The Good Dinosaur)、《伟人》(The Great Man)、《头脑特工队》(Inside Out)、《奋斗的乔伊》(Joy)、《洛杉矶消逝的风景》(Lost Landscapes of Los Angeles)、《魔力麦克2》(Magic Mike XXL)、《办公室》(Office)、《结果》(Results)、《荒野猎人》(The Revenant)、《西默简介》(Seymour: An Introduction)、《小羊肖恩》(Shaun the Sheep Movie)、《女间谍》(Spy)、《冲出康普顿》(Straight Outta Compton)、《橘色》(Tangerine)、《廷巴克图》(Timbuktu)、《生活残骸》(Trainwreck)、《白色上帝》(White God)及《狼群》(The Wolfpack)。
获奖者:加拿大总理贾斯廷·特鲁多
不过,黄金比萨早就不是第一种加入了黄金的食物。“马尼拉社交俱乐部”是纽约威廉斯堡一家菲律宾餐厅,今年早些时候,餐厅老板Bj?rn DelaCruz制作了一款昂贵的黄金水晶宇部甜甜圈。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

channel

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

5.电子烟

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

节目33 歌曲《我爱你中国》,汪峰
*最佳综艺节目台本创作:《约翰?奥利佛上周今夜秀》(Last Week Tonight With John Oliver)

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

According to the National Business Daily, the 16 listed banks plan to return 356.2 billion yuan to shareholders as cash dividends in 2015, a decrease of 8.3 billion yuan from the previous year.
vt. 忽视,疏忽,忽略
布雷克·格里芬
值得庆幸的是,这些户籍规定正在发生改变。12月初,在中国中央经济工作会议上,与会代表建议给予农村居民城市户口,这也强有力地证明了户籍制度正在变化。温家宝总理于12月底呼吁,应加快户籍制度改革的进程。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

泰晤士高等教育世界大学排名的编辑菲尔·巴蒂说,“学校的全球发展前景是一个名牌大学的重要标志之一。顶尖大学聘请来自世界各地的教师,吸引来自全球有极高天分的学生,并能与所有的一流专业合作——不管是哪个国家的。”
Recent years have seen a return of the bacterial infection, reaching numbers not seen since the 1960s, with admissions for a primary diagnosis more than doubling between 2010/11 and 2017/18, from 429 to more than 1,300.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 7月份建材行业运行情况
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Polls indicate that the Dutch election will be extremely tight. Mr Rutte’s centre-right VVD sits atop most polls, just 3 percentage points ahead of the PVV. Most polls show a large percentage of voters remain undecided.
10. 《66》(Sixty Six)。刘易斯·卡尔(Lewis Klahr)把数码短片精彩地汇集在一起,以一种英雄气概的方式复制流行文化,它只在MoMA上映过一晚。但他的作品也在洛杉矶和旧金山等城市上映,所以如果你住在附近,可以去看他的下一次展映。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 做好预调微调 确保稳中向好
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

It grows naturally into the mold's shape.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

英国统计学家不愿纠正RPI服装价格部分的已知错误,每年把巨额资金从学生、新毕业生、纳税人和铁路通勤者重新分配给了与该指数挂钩的英国政府债券持有人、领着与RPI挂钩的退休金的富裕退休金领取人、以及铁路公司。
汉娜库赫勒(Hannah Kuchler)是驻旧金山记者
激情、毅力和积极的心态,是创业成功的关键。培养这些特质要有天赋和一些小技巧。
['hedwei]

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

6.癌症死亡率
That's particularly striking in Brazil, with its highly mixed population that has more blacks than any country with the exception of Nigeria. More than half of Brazil's population self-identified themselves as black or of mixed-race in the 2010 census.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

报告称,2016年共有6.95亿网民使用手机上网,增长率已经连续第三年超过10%。在所有网民中,用智能手机上网的人占比达到了95.1%,而2015年时这一比例还只有90.1%。
What would he try for his solo move: "Sweet Creature" and "Ever Since New York" are intimate acoustic ballads; while "Kiwi" lets him strut his Oasis-style self at top volume. "Two Ghosts" is a break-up lament .
6. 制定计划。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

单词lasting 联想记忆:
3、《丛林故事》
This changed two years ago, though, when Tsinghua University broke into the top 20 for the first time, ranking 18th in 2016. Last year, Peking University joined it in the top 20.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 整理师:家居收纳到整理人生
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

"Twenty Two" featuring the tales of 22 comfort women became the first Chinese documentary to surpass 100 million yuan at the box office.
Some would argue that Carly Simon's theme to The Spy Who Loved Me is the best James Bond theme song ever. They may have a point, but maybe what's really going on is that this is just "the best song from a James Bond movie." It's a fun tune, catchy as hell, romantic and beautifully sung. But nothing about this seems to specifically evoke James Bond, his adventures, his history or even his films. "Nobody Does It Better" is still a winner by any estimation; there's just happens to be a reason why it didn't crack our top five.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

在过去三年里,夏威夷航空公司的航班延误率只有6.92%,几乎是排名第二的阿拉斯加航空公司的一半——这家公司的航班延误率达到11.27%。
Inflation for consumers, meanwhile, ticked up slightly to 1.5 per cent, versus a five-year low of 1.4 per cent in November.
Total Program Cost: $181,500 in either Philadelphia or San Francisco

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The highest average monthly salary for 2016 graduates is 5693 Yuan in IT/Internet/telecommunications/electronics industries; second is financial industry and culture/sports/entertainment/media industries with average salaries level of 4685 Yuan and 4552 Yuan respectively; monthly salaries in agricultural/forest/grassland farming/fishing, and services/ educational sports/industrial arts are relatively low among signed graduates, respectively are 3500 Yuan, 3873 Yuan and 3900 Yuan.
教育企业高管的薪酬均值倒数第一,刚过280万元,约为金融业高管薪酬的1/10。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

一位伦敦软件神童的“硅谷梦”成真,雅虎(Yahoo)斥资近3000万美元收购了他制作的新闻应用。
[p?'tenl]
今年,标普500指数的总回报率为14%,比该指数25年期平均年化收益率高出40%。过去12个月,华尔街的首席战略师们一直在上调其目标值。标普500指数出现了50多次创纪录的收盘,几乎所有专业投资管理人士都卯足了劲,至少要跑平该指数。但有些因素让美股投资者要获得高于基准股指的收益,在今年尤为困难。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

● “女子中彩票后在老板桌上排便被捕”

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Companies that cut support roles during the downturn, the report notes, will be "adding staff to help make departments more productive and efficient." That trend may herald a happy new year for job hunters.
In his report of Global Market of Industrial Robots, Junji Tsuda, president of International Federation of Robotics (IFR), noted that about 387,000 industrial robots were sold in 2017 worldwide, up 31% year-on-year, creating $50 billion in revenue, with China as one of key drivers behind the strong growth.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The Chinese-made 3D fantasy/adventure film "Monster Hunt" broke a string of box-office records on its release in the country in July 2015, becoming the highest grossing film of the year in the Chinese mainland.
其他地方已经出现了这种情况。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

中国上海——上海这座大都市是中国人口最多的城市,在那里,有着深厚历史底蕴的城市核心区与当代全球金融枢纽融为一体。
As computer programming is being hailed as the untapped opportunity in the American economy, New York Code and Design Academy is making it easier to speak code. By 2020 there will be 1.5 million computer science jobs with only 400, 000 computer science graduates. Moreover, computer science jobs are growing at twice the national average as other positions. But what if you didn’t graduate with a computer science degree, and have no plans to go back to college? New York Code and Design Academy is making it easier to learn web design and development by offering both night programs and intensive workshops — where it’s not uncommon for someone to walk out of the program having built a new website or setting sights on a new tech-based position at work. From where Founder Jeremy Snepar sits, you can’t afford to not know how to code in today’s digital economy. He sees coding as a technical skill that can and should be easier to learn, and New York Code and Design Academy is filling an important gap for anyone who’s ever said “if only I knew how to code.”

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Considering Stryker's founder invented the turning frame -- a device that allows patients to be repositioned in bed while keeping their bodies immobile -- it only makes sense that this medical equipment manufacturer lends employees and their families medical beds, free of charge.
独裁者利用前者作为镇压的借口,利用后者要求绝对服从。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Faber laughs at Bernanke's remark that the economy would be strong enough later this year so he could take his foot off the gas, that is begin 'tapering, or scaling back it's stimulative quantitative easing (QE) program later this year.' Yes, laughed.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

但随着美国接近实现充分就业,随着通胀向目标水平趋近,“你可以看到收紧政策是有道理的,”他说,“不需要很多就足以改变整个平衡”。
周期性理论的依据是,新投资不足将导致两三年或五年后出现供应紧张。大量的项目已被延迟,但这对于项目经理而言,不过是要想办法削减成本的一种信号。许多项目经理目前就在这么做。
WASHINGTON: Indiahas trimmed its holdings of US government securities to $77.5 billion at the end of October even as the world's largest economyis expanding at a moderate pace.
Will the BoJ tighten monetary policy

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

作为宝莱坞片酬最高的女演员之一,迪皮卡·帕度柯妮是2015全球十大美女榜的季军。在印度,她是性感女神、时尚偶像。帕度柯妮在印度各类魅力女性榜上的排名都很靠前。完美的身材、深邃的眼神和迷人的微笑使她脱颖而出。她是许多品牌的代言人,包括天梭、索尼数码相机、雀巢咖啡、沃格眼镜、美宝莲和百事可乐等等。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

在经历了艰辛的法律诉讼之后,凯莎发表的一切都会给人一种胜利的假象。但这张回归专辑用艺术反映了一位勇士的呐喊,并带来了比所有人期望中更为强大的影响力。
5)我支持你:我们都犯过大错误。此时,不要回避,要对对方说一些肯定的话语:“我不是在说你不行。你会度过这个难关的。你不是一个人在战斗。我们将一起解决此事。一切都会没事的。”
Inclusive and green finance

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.
“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Hailed as one of the greatest films of all time, Taxi Driver tells the story of a depressed ex-Marine who attempts to assassinate a senator after being rejected by a woman he admires. While the titular taxi driver, Travis Bickle, lives a chaotic life filled with drug dealers and prostitutes, his story was never meant to be an unrealistic fantasy. Rather, it meant to expose the very real warning signs of a would-be gunman.
然而,今年该项目仅排在第8位。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 照明将成智能家居市场主力军
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 重庆:10部门联手遏制投机炒房
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

2.室内类比赛项目

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Explaining how he adjusted the novel, he said: 'I think the answer is that in the book I remain true to every one of Bond's things.
Law
5. Smart belt

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

In addition, the last quarter of 2016 marked the first time that Huawei achieved a double-digit global market share.
However, significantly fewer women (59 per cent) occupy positions as department heads or above than men (68 per cent) three years after graduation.
The wealth and depth of knowledge from around the world adds tremendous value to the course, wrote another graduate from the US, adding that “with so many cultures and experiences represented, a classroom ethics discussion about bribery is not your typical boring USA version”.
《琅琊榜》的意外爆红让这部戏成为2015年秋季档电视剧中的翘楚。同样改编自网络小说(海晏著)的《琅琊榜》2015年9月首播。该剧由胡歌、刘涛等人主演,讲诉了才冠绝伦的谋士梅长苏为昭雪多年冤案进行的一系列斗争。虚构的人物和朝代让改编剧集巧妙地躲过了历史准确性上的责难。它精美的场景布置和无懈可击的故事情节受到了广大观众的一致好评。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

从2015年至2016年,美国ETF市场增长20%,而亚洲市场仅扩大10%。分析师们表示,从两个角度可以看出亚洲ETF市场的规模不及美国和欧洲:后者的市场规模是亚洲的两倍,ETF管理的资产规模为7160亿美元。
在这欢乐的时节给你我最真的祝福和亲切的思念,愿你今年的新年比往年更璀璨。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

The best bosses understand that there must be a balance between the company or client’s needs and the needs of his or her employees. The best bosses are willing to listen and talk about any issues an employee may be having because they understand that a happy employee is a more productive employee。
3.贾君鹏,你妈妈喊你回家吃饭。
2.German: 22.2 percent increase

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Viewers of online live broadcasting can send virtual gifts, which they purchase, to broadcasters. Gifts range from 0.1 yuan to more than 1,000 yuan. A percentage of the money goes to the platform.
4. Jennifer Aniston - $21 million

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