Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Marco Montanari, the head of passive asset management for Asia-Pacific at Deutsche AM, agrees that fundamental changes to distribution must be made before the Asian ETF market can move to the next level.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Domestically, an increasingly active middle class is generating pressure for more accountable governance. Mounting inequalities have nurtured a sense of injustice; 200m migrant workers remain second-class citizens and corruption is worsening. Tackling these problems is urgent, but China's economic successes have fostered an unwarranted self-confidence. Instead, motivated by the Arab spring, the system has moved aggressively to contain any social discontent that might spark more politically sensitive movements.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Trends and targets in antiviral phototherapy
The THE Asia University Rankings for 2017 rated Peking University and Tsinghua University, both in the Chinese capital of Beijing, as the second and third best universities in the continent. National University of Singapore is ranked the best.
Celebrity Latin tattoos may be fuelling a revival of the ancient language in schools, it emerged today。 明星们的拉丁语纹身引发了一阵学习拉丁语的热潮。
Erle Spratt, who manages M&G’s Asia property fund, an open-ended investment vehicle, says it is risky to invest directly because assets are not easy to find and price. “It is a very difficult market to buy assets in for investors like us, because developers have very substantial holdings and they tend not to sell,” he says.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Other Chinese companies that filed a large number of patents included ZTE, Alibaba, Xiaomi, BYD and Haier, all of which are rapidly expanding into Europe.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Meanwhile, a salesman from online travel company Tuniu Corp told the Financial Times that it had on Friday “removed all tours to South Korea due to the Thaad issue”. A search for South Korean tours on the website returns the message: “Sorry, we have not found a relevant product.”
Not every band can sound fresh 40 years into a career, but not every band is Blondie.
Diagnostic technologies for COVID-19: a review
Will the Saudi Aramco public offering debut on an international market
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
However they went ahead with plans to send 100,000 anti-Pyongyang leaflets.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Cousins's deal qualifies as a blockbuster, the Raptors made two strong moves to bolster their contender status, and the race for the West's last playoff spot got far more intriguing, among other storylines.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
"We're excited to have these talented artists showcase the powerful contribution music makes to filmmaking," the show's producers Michael De Luca and Jennifer Todd announced in a statement on Friday. "It's a privilege to welcome them to the 90th Oscars stage."
“One employee’s parents contacted the company to let us know their son was resigning.
Influenza neuraminidase: A druggable target for natural products
According to exam questions and some test-takers' feedback posted online after the exam, the difficulty of the questions was moderate and hot political and social issues, such as the Long March rockets, China's foreign affairs, the Yutu lunar rover and entrepreneurial efforts by college students, were mentioned.
它被广泛误解为一部关于小说家大卫·福斯特·华莱士(David Foster Wallace)的传记电影，其实庞索特的这部影片是一部关于新闻的坏方法的喜剧，以及对文学名誉机制充满了解的辛酸讽刺。杰西·艾森伯格(Jesse Eisenberg)与杰森·西格尔(Jason Segel)使用“男人老友电影”(buddy movie)的传统方式，完美地呈现出一个新的子类：亦敌亦友电影。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
After working for half a year, the average monthly income for 2014 graduates is RMB3,487, a significant increase from RMB3,250 in 2013 and RMB3,048 in 2012.
The role of biosensors in the detection of emerging infectious diseases
The dumbest 'smart' objects of 2016
Quantitative determination of mechanical stability in the novel coronavirus spike protein
日前，斯坦福大学商学院(Stanford Graduate School of Business)教授彼得o库迪斯基于这场荷兰危机共同撰写了一篇文章，围绕“个人经验（而非市场信息）决定乐观、悲观以及信贷的获得与否”这种不那么科学的方法给出了现代经验。
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
“He is very, very good at not allowing that pressure to in any way disrupt what Apple is trying to achieve,” says Mr Iger. “Clearly there were issues that were on his mind but Tim made sure they were never on the minds of the people who do what Apple does best.”
Stand: Wal-Mart U.S. President and CEO Bill Simon pledged to hire veterans
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
For: A huge box office hit that could benefit from a slowly-changing Oscar voting demographic.
Inhibition of SARS coronavirus helicase by bismuth complexes
And regarding Ukraine, the Russian president again denied that there are Russian troops operating inside eastern Ukraine where a pro-Russian separatist movement is fighting Ukrainian government troops. But he said Moscow never denied that "certain people" were there carrying out tasks "in the military sphere." He said Russia plans no sanctions against Ukraine, but will not extend preferential trade to Kyiv.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
China will not see nor allow massive unemployment of particular groups this year, as the government is capable of ensuring a favorable environment to generate jobs.
Length of program: 24 months
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Prince Miteb, who headed the powerful National Guard until early November, was released on November 28th, the official said. At least three other suspects have also finalized settlement deals.
11) I often feel unhappy 0 1 2 3 4
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
I don't know about you, but if I had a separate calendar for work, school and life, I'd be a complete mess. When everything in your life is on one calendar, in one planner, you can't double-book anything. You know, like an important test and a dinner with your boss.
这些新数据是由一个叫做全球碳计划(Global Carbon Project)的追踪项目提交的，发表在了期刊《自然·地球科学》(Nature Geoscience)上。数据公布之际，正是联合国(United Nations)一次峰会召开前夕。此次峰会意在激发新的政治愿望来解决气候变化问题。科学家说，这些数据表明，如果要把长期的全球变暖问题控制在可以承受的范围内，还需要做出极大的努力。
Mr Hoogewerf said that Mr Wang delisted his group’s property arm from the Hong Kong stock exchange this year in the hope of realising a richer valuation for it on the Shanghai or Shenzhen bourse.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
11. 另外26部我喜爱的影片——为什么不呢？其中很多影片本可以跻身我的十佳之列的。《迷失1971》(’71)、《艾米》(Amy)、《失常》(Anomalisa)、《骇客交锋》(Blackhat)、《芝拉克》(Chi-Raq)、《机械姬》(Ex Machina)、《实验者》(Experimenter)、《诉讼》(Gett: The Trial of Viviane Amsalem)、《恐龙当家》(The Good Dinosaur)、《伟人》(The Great Man)、《头脑特工队》(Inside Out)、《奋斗的乔伊》(Joy)、《洛杉矶消逝的风景》(Lost Landscapes of Los Angeles)、《魔力麦克2》(Magic Mike XXL)、《办公室》(Office)、《结果》(Results)、《荒野猎人》(The Revenant)、《西默简介》(Seymour: An Introduction)、《小羊肖恩》(Shaun the Sheep Movie)、《女间谍》(Spy)、《冲出康普顿》(Straight Outta Compton)、《橘色》(Tangerine)、《廷巴克图》(Timbuktu)、《生活残骸》(Trainwreck)、《白色上帝》(White God)及《狼群》(The Wolfpack)。
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
*最佳综艺节目台本创作：《约翰?奥利佛上周今夜秀》(Last Week Tonight With John Oliver)
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
According to the National Business Daily, the 16 listed banks plan to return 356.2 billion yuan to shareholders as cash dividends in 2015, a decrease of 8.3 billion yuan from the previous year.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Recent years have seen a return of the bacterial infection, reaching numbers not seen since the 1960s, with admissions for a primary diagnosis more than doubling between 2010/11 and 2017/18, from 429 to more than 1,300.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Polls indicate that the Dutch election will be extremely tight. Mr Rutte’s centre-right VVD sits atop most polls, just 3 percentage points ahead of the PVV. Most polls show a large percentage of voters remain undecided.
10. 《66》(Sixty Six)。刘易斯·卡尔(Lewis Klahr)把数码短片精彩地汇集在一起，以一种英雄气概的方式复制流行文化，它只在MoMA上映过一晚。但他的作品也在洛杉矶和旧金山等城市上映，所以如果你住在附近，可以去看他的下一次展映。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
It grows naturally into the mold's shape.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
That's particularly striking in Brazil, with its highly mixed population that has more blacks than any country with the exception of Nigeria. More than half of Brazil's population self-identified themselves as black or of mixed-race in the 2010 census.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
What would he try for his solo move: "Sweet Creature" and "Ever Since New York" are intimate acoustic ballads; while "Kiwi" lets him strut his Oasis-style self at top volume. "Two Ghosts" is a break-up lament .
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
This changed two years ago, though, when Tsinghua University broke into the top 20 for the first time, ranking 18th in 2016. Last year, Peking University joined it in the top 20.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
"Twenty Two" featuring the tales of 22 comfort women became the first Chinese documentary to surpass 100 million yuan at the box office.
Some would argue that Carly Simon's theme to The Spy Who Loved Me is the best James Bond theme song ever. They may have a point, but maybe what's really going on is that this is just "the best song from a James Bond movie." It's a fun tune, catchy as hell, romantic and beautifully sung. But nothing about this seems to specifically evoke James Bond, his adventures, his history or even his films. "Nobody Does It Better" is still a winner by any estimation; there's just happens to be a reason why it didn't crack our top five.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Inflation for consumers, meanwhile, ticked up slightly to 1.5 per cent, versus a five-year low of 1.4 per cent in November.
Total Program Cost: $181,500 in either Philadelphia or San Francisco
A modular microarray imaging system for highly specific COVID-19 antibody testing
The highest average monthly salary for 2016 graduates is 5693 Yuan in IT/Internet/telecommunications/electronics industries; second is financial industry and culture/sports/entertainment/media industries with average salaries level of 4685 Yuan and 4552 Yuan respectively; monthly salaries in agricultural/forest/grassland farming/fishing, and services/ educational sports/industrial arts are relatively low among signed graduates, respectively are 3500 Yuan, 3873 Yuan and 3900 Yuan.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Companies that cut support roles during the downturn, the report notes, will be "adding staff to help make departments more productive and efficient." That trend may herald a happy new year for job hunters.
In his report of Global Market of Industrial Robots, Junji Tsuda, president of International Federation of Robotics (IFR), noted that about 387,000 industrial robots were sold in 2017 worldwide, up 31% year-on-year, creating $50 billion in revenue, with China as one of key drivers behind the strong growth.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
The Chinese-made 3D fantasy/adventure film "Monster Hunt" broke a string of box-office records on its release in the country in July 2015, becoming the highest grossing film of the year in the Chinese mainland.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
As computer programming is being hailed as the untapped opportunity in the American economy, New York Code and Design Academy is making it easier to speak code. By 2020 there will be 1.5 million computer science jobs with only 400, 000 computer science graduates. Moreover, computer science jobs are growing at twice the national average as other positions. But what if you didn’t graduate with a computer science degree, and have no plans to go back to college? New York Code and Design Academy is making it easier to learn web design and development by offering both night programs and intensive workshops — where it’s not uncommon for someone to walk out of the program having built a new website or setting sights on a new tech-based position at work. From where Founder Jeremy Snepar sits, you can’t afford to not know how to code in today’s digital economy. He sees coding as a technical skill that can and should be easier to learn, and New York Code and Design Academy is filling an important gap for anyone who’s ever said “if only I knew how to code.”
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Considering Stryker's founder invented the turning frame -- a device that allows patients to be repositioned in bed while keeping their bodies immobile -- it only makes sense that this medical equipment manufacturer lends employees and their families medical beds, free of charge.
A facile assay for rapid detection of COVID-19 antibodies
Faber laughs at Bernanke's remark that the economy would be strong enough later this year so he could take his foot off the gas, that is begin 'tapering, or scaling back it's stimulative quantitative easing (QE) program later this year.' Yes, laughed.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
WASHINGTON: Indiahas trimmed its holdings of US government securities to $77.5 billion at the end of October even as the world's largest economyis expanding at a moderate pace.
Will the BoJ tighten monetary policy
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Inclusive and green finance
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.
“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Hailed as one of the greatest films of all time, Taxi Driver tells the story of a depressed ex-Marine who attempts to assassinate a senator after being rejected by a woman he admires. While the titular taxi driver, Travis Bickle, lives a chaotic life filled with drug dealers and prostitutes, his story was never meant to be an unrealistic fantasy. Rather, it meant to expose the very real warning signs of a would-be gunman.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Explaining how he adjusted the novel, he said: 'I think the answer is that in the book I remain true to every one of Bond's things.
5. Smart belt
Length-scale dependence of protein hydration-shell density
In addition, the last quarter of 2016 marked the first time that Huawei achieved a double-digit global market share.
However, significantly fewer women (59 per cent) occupy positions as department heads or above than men (68 per cent) three years after graduation.
The wealth and depth of knowledge from around the world adds tremendous value to the course, wrote another graduate from the US, adding that “with so many cultures and experiences represented, a classroom ethics discussion about bribery is not your typical boring USA version”.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
The best bosses understand that there must be a balance between the company or client’s needs and the needs of his or her employees. The best bosses are willing to listen and talk about any issues an employee may be having because they understand that a happy employee is a more productive employee。
2.German: 22.2 percent increase
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Viewers of online live broadcasting can send virtual gifts, which they purchase, to broadcasters. Gifts range from 0.1 yuan to more than 1,000 yuan. A percentage of the money goes to the platform.
4. Jennifer Aniston - $21 million