Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
As a result of the country’s strict policies, some of the underwear brand's most famous models are unable to appear in its biggest event of the year with Gigi Hadid announcing that she won’t be attending on Twitter last week.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
6.The Stock Market Plunge
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
China saw its population grow last year, along with an improved male-female ratio and the level of education, according to a survey from the National Bureau of Statistics that was released on last Wednesday.
从该剧2007年首播至今，我们似乎患上了哈德利·弗里曼(Hadley Freeman)在《卫报》(The Guardian)上所称的“广告狂人狂热症”(madmenalaria)。
Trends and targets in antiviral phototherapy
Comic skit “Dance If You Like” (Cai Ming and Pan Changjiang)
‘Veep’ “House of Cards,” the Netflix phenomenon, showed its weaknesses this year, but HBO’s “Veep,” the other most cynical show about Washington, got stronger in its third season. The scene in a restroom in which Selina (Julia Louis-Dreyfus) and her assistant, Gary (Tony Hale) discover that she is going to become president and dissolve into uncontrollable laughter was one of the great comic moments of 2014.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Not only does its small cohort of about 50 allow the school to select highly experienced participants, it also creates a strong bond between them.
Novel biosensing methodologies for ultrasensitive detection of viruses
With another Fast & Furious movie slated to hit theaters next summer, Johnson should have another banner year in 2014. He could do even better thanks to Hercules. The film, about the mythological hero’s life after he completes his famous 12 labors, has franchise potential written all over it. If it’s also a big hit, Johnson’s 2014 box office grosses should be huge.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
1999：H9N2传染人类1999: H9N2 Infects Humans
A series of explosions on Aug. 12 that originated in a warehouse illegally storing hazardous chemicals in the port city of Tianjin killed 173 people, injured hundreds and left behind post-apocalyptic scenes of destruction. The blasts raised serious questions about the lax enforcement of safety regulations during China's rapid industrialization.
ACE2 as a potential therapeutic target for pandemic COVID-19
It is a timely warning. His findings, he writes, “point to a heightened risk of emerging market crises in the coming years as the Fed continues to normalise interest rates”.
Diagnostic technologies for COVID-19: a review
The 22-year-old Lawrence is the face of "The Hunger Games" franchise, and she may earn an Oscar nomination for her performance in "Silver Linings Playbook."
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
新近成立的Eleven James正在男表领域引入合作消费的概念。该公司的会员项目能令你获得亲近一系列精挑细选的高端腕表的机会，这一曾经只和私人飞机、豪华汽车及度假屋联系在一起的会员模式正在Eleven James的手中发扬光大。除腕表外，会员还能注册专享忠诚度项目，其中包括礼宾服务、合伙人利益专享及诸如腕表主题活动等独一无二的体验。听起来有点像男士腕表和飞机租赁公司Net Jets体验的大碰撞？公司创始人兰迪?布兰多夫（Randy Brandoff）在奢侈品营销领域拥有深厚经验，曾经在Net Jets担任高级副总裁和首席营销官、在Marquis Jets担任过执行副总裁和首席营销官。他的专长，加上年复一年增长势头良好的腕表行业，以及一种在其他市场证明行之有效的商业模式——看起来Elven James正是在恰当的时间叩开了市场的大门。
Wang studied computer programming while growing up in China. After college, she hoped to move to the U.S. to start her career. The next year, the Chinese Students Protection Act was passed and Wang got her master's in computer science at University of Houston. She worked at several Silicon Valley startups (and launched her own, iBizWomen.com) until September 11, 2001. The attack inspired her to create Binary Group, a technology consulting company that works with the Federal Government. Over the past 16 years, Binary has helped its clients save piles of money -- like the Army 20th Support Command, which cut $60 million over five years for its satellite communication bandwidth requirements.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Best Companies rank: 1
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
The EU filed just 12 anti-dumping cases in 2015, two less than the year before.
The pear-shaped diamond named The Blue is 13.22 carats is estimated to be worth between $21-$25 million.
Influenza neuraminidase: A druggable target for natural products
Zhang Jingxiu, executive director of Beijing-based employment consultancy Newjincin Research Institute, said he didn't monitor the significant decrease of students' willingness to start businesses, but he does admit the desire to found startups among students on campus is low.
Brazil's President Dilma Rousseff, who is facing impeachment, slashed her own salary by 10% to $103,400 a year last October as part of a wider austerity drive.
具有荷兰和美国双重国籍的Frans de Waal和另一位美国科学家Jennifer Pokorny获得这一奖项，他们的研究确认黑猩猩可以通过辨认同类的屁股照片来认出不同的个体。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Song “The Spring Blossom” (Na Ying)
For: The Los Angeles Critics Association gave it their top prize.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
“The new money is interested in old masters, but it wants what Duveen sold to the robber barons. It wants names,” said Hugo Nathan, a co-founder of the London advisers Beaumont Nathan. He was referring to Joseph Duveen, the British art dealer who was responsible for bringing many great works of art to the United States.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
However, the competition in the finance industry was also fierce. Graduates were advised to start with entry-level jobs and constantly improve their comprehensive capabilities to stay competitive.
But I don't think you can say that to us anymore. Are we even on your list of priorities? My father always says "You are what you do, not what you say." 但我不能再相信这样的话了，孩子们还是你们的优选名单吗？我爸爸总是说：“听其言，观其行，是认识一个人最好的方法”。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Thousands of supporters awaited Rossello’s arrival for the post-swearing-in inauguration ceremony at the island’s seaside Capitol building, clutching umbrellas to protect themselves from a searing sun.
7. Smart cookie oven
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
My heart is my New Year present to you.我的心就是我奉献给你的新年礼物。
Inhibition of SARS coronavirus helicase by bismuth complexes
'I thought I was going to sell the app in the Apple store for a pound or two each, and then I'd use the money to buy a new computer,' says D'Aloisio. 'I'd never had any contact from an investor before. And now here's an email supposedly from a Hong Kong billionaire. It sounded dodgy. I didn't respond the first time. They had to email me again.' D'Aloisio was accompanied by his mother and father ('they were a bit bewildered, it was kind of insane') as he took a meeting with Horizons Ventures's representatives in London in August 2011. The meeting ended with D'Aloisio receiving a seed investment of $300,000.
“It is exceptionally unlikely that we would be witnessing a record year of warmth, during a record-warm decade, during a several decades-long period of warmth that appears to be unrivaled for more than a thousand years, were it not for the rising levels of planet-warming gases produced by the burning of fossil fuels,” Michael E. Mann, a climate scientist at the Pennsylvania State University, said in an email.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Two weeks later, Mr. Bernheimer was among the dozens of long-established old master dealers attending the London evening sales. In the past, they would buy at these auctions to stock up for the Maastricht European Fine Art Fair in March in the Netherlands. But with sellers encouraging Sotheby’s and Christie’s to compete for their business with ever-higher valuations, and auctions now marketed to a shallow pool of wealthy buyers, there was conspicuously little trade bidding.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
As he scanned the Internet for knowledge, D'Aloisio decided that what he really needed was a better way to determine, at a glance, what was worth reading. He envisioned a summarization tool that used language theory to give a meaningful synopsis in fewer than 400 characters.
The hunt for his body began in earnest in 2012 when archaeologists working on historical accounts and geographical clues started to dig beneath the municipal carpark on the spot where Greyfriars was, and found the skeleton.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Captain America: Civil War will hit theatres May 6, 2016. Who's side are you on?
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
"Martial arts are highlighted in the TV series. The actors performed real kung fu," a Douban user Weishenmeyaoxuefa said.
A strong performance in all four rankings for LBS includes first place for its full-time MBA programme and third for both its joint Executive MBA programme (taught with Columbia Business School in the US) and customised executive education.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
'In total I've spent about ￡5,000 in three months on my three girls. One dress cost me $200 and she only wore it twice before she grew out if it - but I don't intend to lower my spending.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Apple Inc.'s Chief Executive Officer Steve Jobs is shown in this combination photo of file photographs dating (top row L to R) July 2000, November 2003, September 2005, (bottom L to R) September 2006, January 2007 and September 2008. Jobs will take a medical leave of absence until the end of June because his health problems are "more complex" than he had thought, shocking investors and sending the company's shares down as much as 10 percent on January 14, 2009.
Wages will finally accelerate after years of stagnation
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
The below are 5 companies that stand out from the rest and are startups to watch in 2014.
Sonneborn, who lives in Bristol, Vermont, with his parents and younger sister, Julia, 11, is seeking the Democratic nomination.
The Family Hub has three internal cameras that connect to your phone to help you see what you do and don't have inside the fridge. So it's basically a $6,000 alternative to classic grocery list written on paper with a pencil.
若原油供应严重中断，仍可能会推高油价，但潜在的供应过剩会降低这种可能性。Saxo Bank的大宗商品策略部门主管汉森(Ole Hansen)说，新兴市场的需求曾使得供应如此紧张，因而任何一次供应中断都造成了油价的大幅波动。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
7.Thought-Controlled Bionic Legs
An Australian woman whose cats ate each other after she abandoned them in her home has been convicted of animal cruelty.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Peace and love for you at New Year from all your students.祝老师新年充满平安和爱。
“This growth is further backed by Video Editing making an appearance at number 3 on the list with a 19% increase,” the report states, “as video content becomes one of the initial draws and call to actions for most customer-focused websites. Heavy video marketing through social media also increases this demand.”
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
"This is something we believe is really important for the future of our country,"Facebook (FB, Fortune 500) CEO Mark Zuckerberg said in August.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Contributing columnist Antoine Gelain is the managing director of Paragon European Partners. He is based in London.
China is preparing to sign more bilateral or multilateral agreements with other countries, and will enhance information exchanges and joint investigation especially with Western countries such as the US, Canada and Australia on some major or individual cases, according to the CCDI.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
In year-on-year terms prices rose in 65 cities and fell in five.
A network of walking and biking trails leads to other lakeside neighborhoods and to downtown, which is about 15 minutes by bicycle and 10 by car. The Walker Art Center and other museums are nearby. Hockey and skating are popular on the lakes in winter; canoeing, swimming and fishing in the summer.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Europe is finally recovering. Japan is also making significant progress. And emerging economies like India, China as well as Indonesia and others, their economic growth rates is likely to be maintained at high levels or likely to accelerate,” he said.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
The UK and France are the two powerhouses of business education in Europe. Nearly half of the schools listed are from either the UK (20) or France (19). French MiMs outperform UK programmes in terms of ranking, salary ($55,000 versus $49,000) and student numbers (9,000 versus 1,200). However, UK MBAs outdo French programmes in terms of numbers (18 schools in this ranking versus five) and student numbers (1,900 versus 1,300) though not in terms of salary ($115,000 versus $137,000).
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Fuel for this latest burst of Tesla mania came from none other than Chairman and CEO Elon Musk in comments he made during an analyst call on July 31. The big news wasn’t that Tesla reported higher production for the second quarter and beat earnings estimates again.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Will emerging market GDP growth pass 5 per cent
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
排行榜上前7所院校还是老面孔。澳大利亚新南威尔士大学商学院(UNSW Business School of Australia)澳大利亚管理研究生院(AGSM)首次上榜，排在第八位。
全食CEO约翰麦基的《自觉资本主义》（Conscious Capitalism）一书让公司高管们不得不思考这样一个观点，那就是处于最佳运转状态的企业能为所有利益相关方创造价值，而不仅仅是投资者。麦基认为，主要利益相关方包括顾客、员工、供应商、社会以及环境。他以好市多、西南航空（Southwest Airlines ，《财富》500强）和谷歌（Google，《财富》500强）为例，说明思维超越利润能够打造更强大而、更高效的公司。
With its goal of universal healthcaresystem coverage by 2020, Chinais expected to transform the medicine market, becoming the second largest afterthe US.In the next five years, Chinaexpects per capita spending to grow by 70 percent.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Meanwhile, producer prices were deflating at a rate of -5.9 per cent, a six-year low, for a third straight month.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
自2007年4月以来，全球最具价值品牌100强的品牌价值增长106%。同期标准普尔500指数(S&P 500)和MSCI明晟全球指数(MSCI world index)分别上涨61%和21%。
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Unfortunately, there won't be a 2014 rematch between Brazil and Uruguay, as the latter was eliminated on Saturday. If Brazil makes it to the final on July 13, the country could play Mexico, the Netherlands, Costa Rica, Greece, USA, Belgium, Argentina or Switzerland.
STEP 6: FIND A WATSON
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
In my country, we make so much waste, we buy and throw away, buy and throw away, and yet northern countries will not share with the needy. Even when we have more than enough, we are afraid to lose some of our wealth, afraid to share. 在我的祖国，我们制造了如此之多的垃圾，我们购买商品，我们随之丢弃，买来，再丢弃。然而有些国家，有些人，却不会分享给那些真正需要的人们，甚至他们拥有的远远超过自身需要的时候。他们害怕分享，害怕失去自己的财富。
He and his girlfriend wrote to each other when he was studying science, he said.They did eventually marry and have four children.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Most of the cellphones sold in 2016 are smart phones installed with the Android system and 4G ready, according to the report.
在这部暂未定名的电影里面，两段交错的三角恋，偏执，背叛等元素与音乐场面相互映衬。参演此片的有克里斯蒂安·贝尔（ChristianBale）、凯特·布兰切特（Cate Blanchett）、迈克尔·法斯宾德（Michael Fassbender）、瑞恩·高斯林（RyanGosling）、鲁妮·玛拉（Rooney Mara）以及娜塔丽·波特曼（Natalie Portman.）。
We will make a big push for progress in the reform of the social system.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
And England ? Well, maybe the best thing to say is that this time, for once, no-one is really expecting anything, and just even getting out of the group is going to be a bonus.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Best Companies rank: 1
Anti-HIV drug repurposing against SARS-CoV-2
8. 斯特吉尔·辛普森(Sturgill Simpson)，《乡村音乐的大现代之声》(Matamodern Sound in Country Music)，High Top Mountain。一支极为聪敏的乐队做出复古的改革：乡村乐中曾经发生过这样的事。但在斯特吉尔·辛普森突破性的第二张专辑中，他把这一点变成了可适应环境的标志，就建立在他那动人而通透的男中音之上。
The website claims that "the more you sip, the smarter you (and the bottle) get," but in reality the more you sip, the drunker you get and the less information you'll retain.
Length-scale dependence of protein hydration-shell density
1. Choosing a job based on compensation alone
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
For parents, it is always a struggle to carry their children all day long, especially when they’re getting bigger and heavier.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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