Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
现在让我们去希腊。在2010年至2015年期间担任希腊统计局(Elstat)局长的安德烈亚斯?耶奥尔耶欧(Andreas Georgiou)，因揭露希腊2009年公共财政虚假数据并更正数据而面临指控。本周，以美国统计协会(American Statistical Association)为首的40个组织和651名个人签署声明，支持耶奥尔耶欧。
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
All three of the big worldwide financial bubbles that have blow up in the last three decades have 'been fueled by the Fed keeping policy rates below the nominal growth rate of the economy far too long, ' says global strategist Kit Juckes of the French bank Societe Generale.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
在排名靠前的学校中，英国华威商学院(Warwick Business School)排名提升最大，从第16位提升至第9名。整体而言，上海交通大学(Shanghai JiaoTong University)的上海高级金融学院(Shanghai Advanced Institute of Finance)排名提升最大，从第28位提升至第14位。
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
As institutions are brought under dictatorial control, the opposition is driven into rebellion or acquiescence.
The FT European Business School Ranking 2016 measures the quality and breadth of schools’ postgraduate programmes. It is based on their performance in the five main rankings published by the Financial Times each year: MBA, Executive MBA (EMBA), Masters in Management (MiM) and the two rankings for executive education. Only schools that take part in all five are eligible for a full score.
“气候变化也许是我们这代人的重大挑战，”美国国家航空航天局(NASA)地球科学部主任迈克尔·H·弗莱利赫(Michael H. Freilich)说，他的部门是跟踪全球气温的机构之一。
Trends and targets in antiviral phototherapy
9) Well Done: It’s a cliché, no doubt. Sometimes, it isn’t enough just to say thanks. People want to know what they did was great and why. They pour so much sweat and soul into their projects.They need to know their work was special and had meaning to someone.
The United Kingdom ranks No. 3 overall. It ranks No. 4 in Power and No. 5 in Cultural Influence.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
"The Constitution really doesn't apply here. The Constitution limits how much government can suppress speech, not a private university," she said.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
The book — published by Basic Books and Oneworld Publications — won out against a strong shortlist dominated by books on technology.
ACE2 as a potential therapeutic target for pandemic COVID-19
But Huy Vo, a senior specialist in public relations at Hawaiian, said the short flights, which make up half the airline’s routes, aren’t all that easy to operate. “Our geographic location certainly does give us an advantage, as well as our short-haul routes, ” Vo said. “However, the short-haul routes are the hardest to keep punctual, because the hops are very short, with brief ground time between flights, so any delay is difficult to make up.
Rouslan Krechetnikov和Hans Mayer对液体的溅出现象进行了研究。他们考察的课题是：人们在端着咖啡杯走动时咖啡的溅出情况，给你个提示吧，在你走到第七步至第十步之间，咖啡最容易溅出。
Diagnostic technologies for COVID-19: a review
In one example, Christie’s was offering the mid-18th-century canvas “Rebecca and Eliezer at the Well” by the Venetian artist Francesco Fontebasso at a low estimate of 120,000. The pleasant piece of rococo decoration had been bought at auction in 1990 for $286,000, according to Artnet. At the Dec. 8 sale it fell to a single telephone bid of 115,000, about $170,000, before fees. Investors do not expect to incur a loss of about 40 percent a quarter century after buying a Warhol or a Basquiat. Reselling an old master can be even harder when that painting has been languishing in a dealer’s gallery.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
A child prodigy with an IQ higher than Albert Einstein is celebrating becoming a unique member of Mensa. Nishi Uggalle, ten, is one of the youngest people in the country to score the highest possible mark of 162 in the IQ society's supervised testing.
China Mobile, supply chain rumors are emerging about Apple’s next significant product releases. Digitimes reports that according to “sources from the upstream supply chain, ” Apple is planning to release a 5-inch iPhone 6 “phablet” this coming May and a large tablet in October.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
As supporters kept streaming toward the Capitol building, one yelled out, “Today, a new Puerto Rico begins!” to the cheers of others, including those holding U.S. flags.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
实际上，去年新出炉的炒鱿鱼委婉用语(euphemisms for firing people)跟往年的产量差不多。Infosys宣称“井然有序地实现了一次3000人的人员递减”。Upworthy，一家规模不大的媒体公司，在解雇了14名员工后竟然大言不惭地称这是一次“投资性裁员”。反言之，2016年最极品的行话体现出的不是失败，而是兴奋过头。
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Committee Chairman Thorbjoern Jagland praised the work of the three recipients, saying that "we cannot achieve lasting peace in the world unless women obtain the same opportunities as men."
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
“…was caught in a big lie on her resume during the meeting.”
'For what is really exceptional, not seen on the market, there are really clients looking for such investments,'
Influenza neuraminidase: A druggable target for natural products
China’s official producer price index rose 1.2 per cent year-on-year in October, according to the National Bureau of Statistics, marking the second straight month of rising prices after 53 months of annualised contraction finally ended in September.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
No.1: Einstein Alive Again?
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
It is also argued that Friends came about as the family unity of small-town America was being replicated in major urban centers as young people migrated without the maturity or streetsmarts to live alone. Before Friends, sitcoms tended to focus on family dynamics, with parents being the central characters. But when young people strike out on their own in the big city, who do they have for support? They must rely on each other to endure through the overwhelming confusion of youth.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
The company advises consumers or businesses using any of the passwords on the list to change them immediately. Splashdata warned that even passwords with common substitutions like "dr4mat1c" can be vulnerable to attackers' increasingly sophisticated technology.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Jennifer Lawrence also took home the gong for best actress in a movie for her role in the critical darling Joy.
However, you know when your cycles are over when the washer and dryer stop making noise. And you know when the weather is ugly by simply looking outside, or checking your weather app. Therefore, the product is basically just another way hackers can get into your home.
Inhibition of SARS coronavirus helicase by bismuth complexes
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
1. World Health Organisation declares a public emergency of international concern over Zika
The Chinese-made 3D fantasy/adventure film "Monster Hunt" broke a string of box-office records on its release in the country in July 2015, becoming the highest grossing film of the year in the Chinese mainland.
Meanwhile, in recent months mainland investors have been rapidly owning equity trading accounts and putting money into the stock market. The Shanghai Composite has become the region's best performing index, rising nearly 45 per cent year to date.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
EMBAGlobal is the only programme in the top 10 that saw a slight drop in the average salary of its alumni compared with last year (the other nine recorded strong increases).
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Master of None
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Mazda wins the award for Best Car Brand. The automotive press has always loved Mazdas for their performance, but the Mazda cars on the road today earn positive reviews for their well-made interiors as well as their athletic driving dynamics. The 2016 Mazda3, pictured here, is in the top tier of the U.S. News compact car rankings, with most car reviewers recommending it for its nimble handling, strong acceleration and upscale interior.
Alfonso Cuaron and his colleagues, most notably the cinematographer Emmanuel Lubezki, the production designer Andy Nicholson and the filmmaker's co-writer, Jonas Cuaron, have made a motion picture that expands the way motion pictures will be made. Readers with an interest in technology can get a sense of their extraordinary achievements from last month's cover story of American Cinematographer, which is available online. But the emotional essence of the film is already known to anyone who has seen it, and has been swept away by it-into the outer space of silence and menace, into an inner space of deep delight.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
At school, even in kindergarten, you teach us to behave in the world. You teach us: not to fight with others, to respect others, to clean up our mess, not to hurt other creatures, to share - not be greedy. 在学校，甚至在幼稚园，你们大人教我们如何处世，你们告诉我们不要打架，要尊重对方。找出答案，解决矛盾。去分享，而不是贪婪。
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Russia regards itself as a great power - it is not in question anywhere inside the country.
It is a struggle for power contained by understandings and institutions.
Are you ready for a summer scare? Conjuring 2: The Enfield Poltergeist is set to hit the screens on June 10, 2016. We reckon that this is going to be a good horror movie.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
How are your competitors getting found online? Google Adwords Keyword Planner helps you answer this question. The word “Adwords” may give some ‘treps pause, as it sounds like you will have to purchase advertising. Not true. Google has made its Keyword Planner tool available to anyone with a Google account (you must first click through the Adwords entry portal). Use the Adwords Keyword Planner to see what keywords are generating the most search volume in your niche and identify opportunities to capture traffic.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
在本届达沃斯世界经济论坛(World Economic Forum)盛大闭幕会议上，与会者承认风险的存在，认为缺乏有效管理的新兴市场很容易受到危机冲击，但他们最终得出的结论是，前景是多年来最为光明的。
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The gold market may be obsessed about the dollar and prospect of a rise in US interest rates. But there’s another factor looming on the horizon: a fall in gold mine supply.
Meanwhile, there are other factors holding back the Asian ETF market that some sceptics fear will hold back development of the retail side.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
McDonald's (MCD, Fortune 500), the all-American fast food Mecca, announced it would put $20 billion towards share repurchases and dividends Thursday, jumping on board the buyback trend that has boomed over the past 18 months.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Exports to both South Korea and Asean countries fell by about 3 per cent, however, while those to re-exporter Hong Kong dropped by more than 16 per cent.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
联系方式：Kathy Michalove, Seaboard Properties, (860) 535-8364; seaboardpropertiesre.com
You can browse the full list at AskMen.com. Here are the top 10 women:
Moonlight, an evocative coming of age story about a young gay black man, won best picture at the 2017 Oscars but was almost denied its victory in chaotic scenes when the award was mistakenly given to La La Land.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
约瑟夫?斯蒂格利茨(Joseph Stiglitz)等诺贝尔经济学奖得主、比尔?麦吉本(Bill McKibben)等环保活动人士、乔治?索罗斯(George Soros)及新经济思维研究所(Institute for New Economic Thinking)、阿尔?戈尔(Al Gore)和其他现代思想家全都提醒我们，传统经济学家（以及他们效力的银行、企业和政府机构）都已对坏的经济学理论成瘾，他们在破坏美国的未来。
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Wang Chunfa, executive secretary of the China Association for Science and Technology, has expressed deep concern over the retraction, which came just days after he met in Beijing with Arnout Jacobs, the head of Springer Nature for Greater China.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
White people’s officially privileged status waned over the latter half of the 20th century with the demise of discriminatory practices in, say, university admissions. But rising wages, an expanding social safety net and new educational opportunities helped offset that. Most white adults were wealthier and more successful than their parents, and confident that their children would do better still.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Misrepresenting your credentials or intentionally plagiarizing, lying on time sheets or billable hours, misusing expense accounts or abusing company credit cards, stealing the kudos for a co-workers' accomplishments, or otherwise robbing your employers blind can all cost you your job.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
HEC Paris and London Business School have tightened their grip on the top of the Financial Times rankings of pre-experience and post-experience Masters in Finance programmes respectively, having dominated the finance rankings since they were first published in 2011.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
However, before starting their EMBAs, there is already a wide gap in salaries, with women earning on average 15 per cent less than men, at $111,000 and $128,000 respectively.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The dip for the Caixin gauge, which concentrates on smaller and private manufacturers, stands in contrast to a pickup for China’s official manufacturing PMI, which focuses primarily on large, state-owned enterprises. The divergence may indicate that smaller outfits have been hit harder by pollution curbs and other regulatory tightening than their larger, state-run competitors, which also enjoy privileged access to state-run lenders.
A total of 3,077 new cases of HIV infection took place in colleges and universities across China in 2017, according to the National Health Commission (NHC) at a press conference on Friday.
A facile assay for rapid detection of COVID-19 antibodies
6. A brand new human organ has been classified. Researchers have given the nod to the mesentery - an organ that's been hiding in plain sight in our digestive system this whole time. But that's only half the story, because we're still not sure exactly what it does.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Despite the promise of downloadable courses, teaching for officially recognised qualifications continues to be a classroom-based activity undertaken in the real world. Start-ups have taken the attitude that if they cannot beat the universities and colleges at their own game with new methods of delivery, they should join them in partnerships. As a result, they have been busy getting examining boards to endorse their online courses so that they can count towards a bachelor’s or master’s qualification.
What the government should do is to send a resounding message of “yes” to the all law-abiding market entities, to flash the green light of going ahead to the hardworking entrepreneurs and innovators, and to seriously deal with all violations of laws and regulations by showing them a resolutely a “yellow card” of stern warning, or even a “red card” to send them out of the market.
When Finnish programmer Jerry Jalava had a motorcycle accident in 2008, he faced a double tragedy. First, he lost his finger, an obvious problem for anyone who types for a living. Second, he had to deal with a medical team who thought they were comedians—learning of his profession, one surgeon joked that Jalava should go out and buy a “USB finger drive.”
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
The number of university graduates reached 7.65 million in 2016, hitting a new historic high, the Beijing News reported. Plus, the number of students graduating from secondary vocational schools hit 4.35 million, bringing the total figure to 12 million.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
The China Association of Automobile Manufacturers announced on Friday that passenger car sales totaled 2.2 million units in January, 9.3 percent more than a year earlier, and the production of new-energy vehicles surged by 144 percent.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
3.Sit in the Front Row
Anti-HIV drug repurposing against SARS-CoV-2
“I thought it would be impossible to replace Steve, and to some extent that’s true,” says Professor Michael Cusumano of MIT’s Sloan School of Management. “But internally the spirit is still alive and the company is organising around a less confrontational culture. We have to give Tim credit for that.”
6. “Taxi”(Jafar Panahi)
Tony Moloney, head of education and skills at National Grid, says the UK utility’s involvement is part of its broader strategy to encourage school students to study Stem subjects — science, technology, engineering and mathematics — and learn more about jobs in his sector.
Length-scale dependence of protein hydration-shell density
In August, the holdings were to the tune of $80.4 billion while it stood at $79.7 billion in July.
除了北方高等商学院和巴黎高等商学院以外，高等经济商业学院(Essec Business School)、巴黎高等商业学院-欧洲管理学院(ESCP Europe)和商科联盟国际商学院(Skema Business School)分列第三、第四和第六位。
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
That Apple could launch a 2,000 yuan ($330) iPhone mini and be competitive with flagship products from Lenovo, Huawei, ZTE and Coolpad.
《Look What You Made Me Do》（《看看你们都让我做了什么》）这首单曲可以载入史册了，流行音乐学者们可能会世世代代地讨论它是否是一次绝妙的公关行动。
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
This slide in the dollar value of exports has entirely been a price effect, driven by lower commodity prices. In volume terms, emerging market exports have continued to rise since 2014, even if volume growth in year-on-year terms has moderated to around 2 per cent, a fraction of the double-digit rates witnessed either side of the global financial crisis, as the second chart shows.
About this collection
Length of program: 19 months